UniProt:P08582 MELTF

chain
  • signal peptide:1-19
  • chain:20-709
  • propeptide:710-738
checksum B0F08B708D2A0A0F
comment
  • FUNCTION Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.INTERACTION Found predominantly in human melanomas and in certain fetal tissues; also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts.SIMILARITY Belongs to the transferrin family.
crossReference
databaseName UniProt
dbId 66403
description
  • recommendedName: fullName evidence="8"Melanotransferrin alternativeName: Melanoma-associated antigen p97 cdAntigenNameCD228/cdAntigenName
displayName UniProt:P08582 MELTF
geneName
  • MELTF
  • MAP97
  • MFI2
identifier P08582
isSequenceChanged false
keyword
  • 3D-structure
  • Alternative splicing
  • Cell membrane
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • GPI-anchor
  • Ion transport
  • Iron
  • Iron transport
  • Lipoprotein
  • Membrane
  • Metal-binding
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Signal
  • Transport
  • Zinc
modified [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType Protein
name
  • MELTF
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • TRFM_HUMAN
  • Q9BQE2
sequenceLength 738
species [Species:48887] Homo sapiens
stId uniprot:P08582
url http://purl.uniprot.org/uniprot/P08582
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