Reactome | UniProt:P05748 RPL15A

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UniProt:P05748 RPL15A Show undefined attributes

chain	initiator methionine:1 chain:2-204
checksum	3913F9E4AB9ECA2C
comment	FUNCTION Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.SUBUNIT Component of the large ribosomal subunit (LSU). Mature yeast ribosomes consist of a small (40S) and a large (60S) subunit. The 40S small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33 different proteins (encoded by 57 genes). The large 60S subunit contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different proteins (encoded by 81 genes) (PubMed:22096102, PubMed:9559554).SUBCELLULAR LOCATION There are 2 genes for eL15 in yeast.SIMILARITY Belongs to the eukaryotic ribosomal protein eL15 family.
crossReference	[DatabaseIdentifier:12144955] PDB:6QT0 [DatabaseIdentifier:12444043] RefSeq:NP_013129.1 [DatabaseIdentifier:12259789] PRO:P05748 [DatabaseIdentifier:12144998] PDB:7UQZ [DatabaseIdentifier:12142347] PDB:3J6X [DatabaseIdentifier:12142319] PDB:4V88 [DatabaseIdentifier:12142389] PDB:8CKU [DatabaseIdentifier:12144981] PDB:7UQB [DatabaseIdentifier:12144986] PDB:8AGZ [DatabaseIdentifier:12142338] PDB:8Z70 [DatabaseIdentifier:12142371] PDB:8ZGR [DatabaseIdentifier:12142336] PDB:4V8Z [DatabaseIdentifier:12142341] PDB:7MPJ [DatabaseIdentifier:12150882] PDB:7R7A [DatabaseIdentifier:12142308] PDB:4U4Z [DatabaseIdentifier:12152564] PDB:8PFR [DatabaseIdentifier:12145007] PDB:6N8L [DatabaseIdentifier:12144988] PDB:8BIP [DatabaseIdentifier:12145004] PDB:6N8K [DatabaseIdentifier:12145000] PDB:8HFR [DatabaseIdentifier:12144977] PDB:7TOP [DatabaseIdentifier:12145002] PDB:8BJQ [DatabaseIdentifier:12142364] PDB:6XIQ [DatabaseIdentifier:12145001] PDB:6M62 [DatabaseIdentifier:12144993] PDB:5APO [DatabaseIdentifier:12142327] PDB:5MEI [DatabaseIdentifier:12144989] PDB:8AGT [DatabaseIdentifier:12142362] PDB:6XIR [DatabaseIdentifier:12142339] PDB:8CIV [DatabaseIdentifier:12150880] PDB:6C0F [DatabaseIdentifier:12142356] PDB:8ZGY [DatabaseIdentifier:12144979] PDB:6YLG [DatabaseIdentifier:12142400] PDB:5DGV [DatabaseIdentifier:12144997] PDB:6S05 [DatabaseIdentifier:12142404] PDB:5DGF [DatabaseIdentifier:12144996] PDB:7OF1 [DatabaseIdentifier:12142332] PDB:8K82 [DatabaseIdentifier:12153839] PDB:7OSM [DatabaseIdentifier:12144983] PDB:5T62 [DatabaseIdentifier:12142346] PDB:3J78 [DatabaseIdentifier:12142321] PDB:6TNU [DatabaseIdentifier:12142420] PDB:8CMJ [DatabaseIdentifier:12139467] PDB:4V91 [DatabaseIdentifier:12144973] PDB:6FT6 [DatabaseIdentifier:12145008] PDB:6N8O [DatabaseIdentifier:12142424] PDB:5TGM [DatabaseIdentifier:12150868] PDB:7U0H [DatabaseIdentifier:12142348] PDB:3J6Y [DatabaseIdentifier:12144985] PDB:8AGW [DatabaseIdentifier:12142315] PDB:4U6F [DatabaseIdentifier:12144978] PDB:6YLH [DatabaseIdentifier:12142353] PDB:8ZHC [DatabaseIdentifier:12144991] PDB:6OIG [DatabaseIdentifier:12142314] PDB:8CGN [DatabaseIdentifier:12142344] PDB:7MPI [DatabaseIdentifier:12144971] PDB:6QIK [DatabaseIdentifier:12140535] PDB:8Z71 [DatabaseIdentifier:12144990] PDB:8AGU [DatabaseIdentifier:12144984] PDB:8AGV [DatabaseIdentifier:12142357] PDB:3J77 [DatabaseIdentifier:12151498] PDB:5Z3G [DatabaseIdentifier:12142320] PDB:5DAT [DatabaseIdentifier:12142307] PDB:4U4Y [DatabaseIdentifier:12145005] PDB:6N8J [DatabaseIdentifier:12142368] PDB:6TB3 [DatabaseIdentifier:12144987] PDB:6YLY [DatabaseIdentifier:12151499] PDB:6CB1 [DatabaseIdentifier:12144975] PDB:7UOO [DatabaseIdentifier:12142403] PDB:5DGE [DatabaseIdentifier:12142351] PDB:8ZHB [DatabaseIdentifier:12142325] PDB:6HHQ [DatabaseIdentifier:12142345] PDB:6SNT [DatabaseIdentifier:12144999] PDB:5T6R [DatabaseIdentifier:12144980] PDB:7TOO [DatabaseIdentifier:12145012] PDB:5JCS [DatabaseIdentifier:12144976] PDB:7V08 [DatabaseIdentifier:12142334] PDB:4V8Y [DatabaseIdentifier:12144974] PDB:3JCT [DatabaseIdentifier:12142383] PDB:8P4V [DatabaseIdentifier:12144972] PDB:4V8T [DatabaseIdentifier:12142394] PDB:5TGA [DatabaseIdentifier:12150862] PDB:7NAC [DatabaseIdentifier:12142342] PDB:7NRC [DatabaseIdentifier:12144994] PDB:5APN [DatabaseIdentifier:12144992] PDB:7AZY [DatabaseIdentifier:12142423] PDB:5ON6 [DatabaseIdentifier:12145011] PDB:7OH3 [DatabaseIdentifier:12142391] PDB:8XU8 [DatabaseIdentifier:12142372] PDB:8ZH3 [DatabaseIdentifier:12144982] PDB:8AGX [DatabaseIdentifier:12142330] PDB:5TBW [DatabaseIdentifier:12142407] PDB:6T4Q [DatabaseIdentifier:12145010] PDB:6N8N [DatabaseIdentifier:12142312] PDB:6Q8Y [DatabaseIdentifier:12153840] PDB:7OSA [DatabaseIdentifier:12142322] PDB:9F9S [DatabaseIdentifier:12142313] PDB:5DC3 [DatabaseIdentifier:12144995] PDB:6YLX [DatabaseIdentifier:12145006] PDB:6N8M [DatabaseIdentifier:12142343] PDB:7NRD [DatabaseIdentifier:12142379] PDB:8EVP [DatabaseIdentifier:12142349] PDB:8EWB [DatabaseIdentifier:12150861] PDB:7BTB [DatabaseIdentifier:12140964] PDB:4V5Z [DatabaseIdentifier:12142410] PDB:4U50 [DatabaseIdentifier:12142421] PDB:8CEH [DatabaseIdentifier:12142417] PDB:4U53 [DatabaseIdentifier:12142416] PDB:4U4R [DatabaseIdentifier:12150872] PDB:7BT6 [DatabaseIdentifier:12142412] PDB:5NDG [DatabaseIdentifier:12142301] PDB:5NDW [DatabaseIdentifier:12142363] PDB:8EVQ [DatabaseIdentifier:12142415] PDB:7ZW0 [DatabaseIdentifier:12142306] PDB:4U56 [DatabaseIdentifier:12152563] PDB:4V4B [DatabaseIdentifier:12142382] PDB:6Z6K [DatabaseIdentifier:12150864] PDB:6ELZ [DatabaseIdentifier:12142292] PDB:8CG8 [DatabaseIdentifier:12151497] PDB:8E5T [DatabaseIdentifier:12144966] PDB:6RI5 [DatabaseIdentifier:12144968] PDB:6RZZ [DatabaseIdentifier:12145960] PDB:8V87 [DatabaseIdentifier:12142365] PDB:8EVR [DatabaseIdentifier:12142397] PDB:4U3M [DatabaseIdentifier:12142413] PDB:4U4Q [DatabaseIdentifier:12142359] PDB:8T3A [DatabaseIdentifier:12145958] PDB:8V84 [DatabaseIdentifier:12142366] PDB:8T3E [DatabaseIdentifier:12142354] PDB:6GQ1 [DatabaseIdentifier:12142298] PDB:5MC6 [DatabaseIdentifier:12151495] PDB:7R6Q [DatabaseIdentifier:12144969] PDB:4V7F [DatabaseIdentifier:12142418] PDB:5M1J [DatabaseIdentifier:12151496] PDB:6EM4 [DatabaseIdentifier:12151494] PDB:6EM3 [DatabaseIdentifier:12140536] PDB:8YLR [DatabaseIdentifier:12142396] PDB:8PNN [DatabaseIdentifier:12142414] PDB:4U52 [DatabaseIdentifier:12144963] PDB:6R87 [DatabaseIdentifier:12142385] PDB:8CCS [DatabaseIdentifier:12144967] PDB:8AAF [DatabaseIdentifier:12142384] PDB:6Z6J [DatabaseIdentifier:12142380] PDB:7ZRS [DatabaseIdentifier:12150869] PDB:6EM5 [DatabaseIdentifier:12142303] PDB:4U55 [DatabaseIdentifier:12144959] PDB:7ZS5 [DatabaseIdentifier:12142408] PDB:4U4N [DatabaseIdentifier:12142402] PDB:5FCI [DatabaseIdentifier:12142299] PDB:5NDV [DatabaseIdentifier:12144964] PDB:6R86 [DatabaseIdentifier:12144960] PDB:6QTZ [DatabaseIdentifier:12142388] PDB:6GQV [DatabaseIdentifier:12140531] PDB:7B7D [DatabaseIdentifier:12142422] PDB:4U3U [DatabaseIdentifier:12144954] PDB:7UG6 [DatabaseIdentifier:12142350] PDB:8EWC [DatabaseIdentifier:12142335] PDB:7N8B [DatabaseIdentifier:12144956] PDB:9F58 [DatabaseIdentifier:12150863] PDB:8V83 [DatabaseIdentifier:12142419] PDB:4V6I [DatabaseIdentifier:12142411] PDB:4U51 [DatabaseIdentifier:12142392] PDB:6GQB [DatabaseIdentifier:12154598] PDB:7R6K [DatabaseIdentifier:12142399] PDB:4U3N [DatabaseIdentifier:12142393] PDB:8K2D [DatabaseIdentifier:12142340] PDB:8T30 [DatabaseIdentifier:12142378] PDB:5OBM [DatabaseIdentifier:12142337] PDB:7ZPQ [DatabaseIdentifier:12144957] PDB:5H4P [DatabaseIdentifier:12144961] PDB:7Z34 [DatabaseIdentifier:12142305] PDB:4U4U [DatabaseIdentifier:12142360] PDB:8EVT [DatabaseIdentifier:12142358] PDB:8EVS [DatabaseIdentifier:12142300] PDB:6I7O [DatabaseIdentifier:12142426] PDB:7ZUW [DatabaseIdentifier:12142375] PDB:8T2X [DatabaseIdentifier:12144962] PDB:6R84 [DatabaseIdentifier:12142352] PDB:8BQD [DatabaseIdentifier:12142381] PDB:8T2Z [DatabaseIdentifier:12142329] PDB:6T7I [DatabaseIdentifier:12144965] PDB:6HD7 [DatabaseIdentifier:12142409] PDB:4U4O [DatabaseIdentifier:12142405] PDB:8CF5 [DatabaseIdentifier:12142374] PDB:6WOO [DatabaseIdentifier:12142333] PDB:8P9A [DatabaseIdentifier:12142331] PDB:5I4L [DatabaseIdentifier:12142401] PDB:8CDL [DatabaseIdentifier:12142395] PDB:5FCJ [DatabaseIdentifier:12142367] PDB:8T3F [DatabaseIdentifier:12142425] PDB:7ZUX [DatabaseIdentifier:12142398] PDB:8CDR [DatabaseIdentifier:11507222] ENSEMBL:YLR029C [DatabaseIdentifier:11620851] ENSEMBL:YLR029C [DatabaseIdentifier:11743550] ENSEMBL:YLR029C_mRNA [DatabaseIdentifier:12142324] PDB:8EUB [DatabaseIdentifier:12142316] PDB:8BN3 [DatabaseIdentifier:12150876] PDB:7OHV [DatabaseIdentifier:12142295] PDB:5JUU [DatabaseIdentifier:12150877] PDB:7OHW [DatabaseIdentifier:12142294] PDB:5JUS [DatabaseIdentifier:12142304] PDB:5LYB [DatabaseIdentifier:12150875] PDB:7OHP [DatabaseIdentifier:12150879] PDB:7OHU [DatabaseIdentifier:12140532] PDB:8YLD [DatabaseIdentifier:12142328] PDB:8UTI [DatabaseIdentifier:12142296] PDB:5JUT [DatabaseIdentifier:12150871] PDB:7OHY [DatabaseIdentifier:12142309] PDB:6SV4 [DatabaseIdentifier:12142323] PDB:6T83 [DatabaseIdentifier:12142326] PDB:6T7T [DatabaseIdentifier:12142293] PDB:5JUP [DatabaseIdentifier:12152562] PDB:8P8M [DatabaseIdentifier:12142311] PDB:8UT0 [DatabaseIdentifier:12150873] PDB:7OHR [DatabaseIdentifier:12153837] PDB:7RR5 [DatabaseIdentifier:12152561] PDB:8P8N [DatabaseIdentifier:12142302] PDB:5JUO [DatabaseIdentifier:12144953] PDB:5GAK [DatabaseIdentifier:12144951] PDB:7OHQ [DatabaseIdentifier:12150874] PDB:7OHS [DatabaseIdentifier:12142318] PDB:6S47 [DatabaseIdentifier:12150870] PDB:7OHX [DatabaseIdentifier:12142297] PDB:8P85 [DatabaseIdentifier:12144952] PDB:8P8U [DatabaseIdentifier:12142290] PDB:4V7R [DatabaseIdentifier:12142377] PDB:8T2Y [DatabaseIdentifier:12150866] PDB:6EM1 [DatabaseIdentifier:12142361] PDB:8T3B [DatabaseIdentifier:12142370] PDB:8T3D [DatabaseIdentifier:12144970] PDB:8Y0U [DatabaseIdentifier:12142369] PDB:8T3C [DatabaseIdentifier:12142386] PDB:8BQX
databaseName	UniProt
dbId	99432
description	recommendedName: fullName evidence="5"Large ribosomal subunit protein eL15A alternativeName: fullName evidence="6"60S ribosomal protein L15-A alternativeName: L13 alternativeName: RP15R alternativeName: YL10 alternativeName: YP18
displayName	UniProt:P05748 RPL15A
geneName	RPL15A RPL10A RPL13A YL10A YLR029C
identifier	P05748
isSequenceChanged	false
keyword	3D-structure Cytoplasm Direct protein sequencing Reference proteome Ribonucleoprotein Ribosomal protein
modified	[InstanceEdit:9963647] Weiser, Joel, 2025-08-15
moleculeType	Protein
name	RPL15A
otherIdentifier	850716 GO:0002181 GO:0003723 GO:0003735 GO:0005198 GO:0005575 GO:0005737 GO:0005829 GO:0005840 GO:0006412 GO:0022625 GO:1990904
physicalEntity	[EntityWithAccessionedSequence:R-SCE-72416] RPL15A [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-9633079] RPL15A [cytosol] - Saccharomyces cerevisiae
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:11372431] BioGPS Gene:850716 RPL15A [ReferenceDNASequence:12707148] UCSC:P05748 RPL15A [ReferenceDNASequence:11910387] KEGG:sce:YLR029C RPL15A [ReferenceDNASequence:12002220] Monarch:850716 RPL15A [ReferenceDNASequence:12086313] NCBI Gene:850716 RPL15A
referenceTranscript	[ReferenceRNASequence:12625595] RefSeq:NM_001181916.1 RPL15A
schemaClass	ReferenceGeneProduct
secondaryIdentifier	RL15A_YEAST D6VY31
sequenceLength	204
species	[Species:68322] Saccharomyces cerevisiae
stId	uniprot:P05748
url	http://purl.uniprot.org/uniprot/P05748

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