Reactome | UniProt:P04792 HSPB1

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UniProt:P04792 HSPB1 Show undefined attributes

chain	chain:1-205
checksum	1B4DC44A6F6606D5
comment	FUNCTION Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state (PubMed:10383393, PubMed:20178975). Plays a role in stress resistance and actin organization (PubMed:19166925). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed:23728742).SUBUNIT Homooligomer (PubMed:10383393). Homodimer; becomes monomeric upon activation (PubMed:20178975). Heterooligomer; with HSPB6 (PubMed:23948568). Associates with alpha- and beta-tubulin (PubMed:10777697). Interacts with TGFB1I1 (By similarity). Interacts with CRYAB (PubMed:1560006). Interacts with HSPB8 (PubMed:11342557). Interacts with HSPBAP1 (PubMed:10751411).INTERACTION Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.TISSUE SPECIFICITY Detected in all tissues tested: skeletal muscle, heart, aorta, large intestine, small intestine, stomach, esophagus, bladder, adrenal gland, thyroid, pancreas, testis, adipose tissue, kidney, liver, spleen, cerebral cortex, blood serum and cerebrospinal fluid. Highest levels are found in the heart and in tissues composed of striated and smooth muscle.INDUCTION Up-regulated in response to environmental stresses such as heat shock (PubMed:8325890). Up-regulated by estrogen stimulation (PubMed:2743305).INDUCTION (Microbial infection) Up-regulated in response to enterovirus 71 (EV71) infection (at protein level).PTM Phosphorylated upon exposure to protein kinase C activators and heat shock (PubMed:8325890). Phosphorylation by MAPKAPK2 and MAPKAPK3 in response to stress dissociates HSPB1 from large small heat-shock protein (sHsps) oligomers and impairs its chaperone activity and ability to protect against oxidative stress effectively. Phosphorylation by MAPKAPK5 in response to PKA stimulation induces F-actin rearrangement (PubMed:1332886, PubMed:19166925, PubMed:8093612).DISEASE The disease is caused by variants affecting the gene represented in this entry.DISEASE The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the small heat shock protein (HSP20) family.
crossReference	[DatabaseIdentifier:11447235] ENSEMBL:ENSG00000106211 [DatabaseIdentifier:12817016] ZINC target:P04792 [DatabaseIdentifier:12813599] ZINC - Substances:HSPB1_HUMAN [DatabaseIdentifier:12809730] ZINC - Predictions - Purchasable:HSPB1_HUMAN [DatabaseIdentifier:12806404] ZINC - Investigational:HSPB1_HUMAN [DatabaseIdentifier:12314723] RefSeq:NP_001531.1 [DatabaseIdentifier:12283157] Pharos - Targets:P04792 [DatabaseIdentifier:12241479] PRO:P04792 [DatabaseIdentifier:12164203] PDB:3Q9P [DatabaseIdentifier:12164201] PDB:6DV5 [DatabaseIdentifier:12164200] PDB:2N3J [DatabaseIdentifier:12164204] PDB:3Q9Q [DatabaseIdentifier:12164202] PDB:6GJH [DatabaseIdentifier:12164205] PDB:4MJH [DatabaseIdentifier:12137496] Orphanet:HSPB1 [DatabaseIdentifier:12122838] OpenTargets:ENSG00000106211 [DatabaseIdentifier:11838330] HPA:ENSG00000106211-HSPB1 [DatabaseIdentifier:11800764] GlyGen:P04792 [DatabaseIdentifier:11785247] GeneCards:HSPB1 [DatabaseIdentifier:11657739] ENSEMBL:ENST00000248553 [DatabaseIdentifier:11535040] ENSEMBL:ENSP00000248553
databaseName	UniProt
dbId	56678
description	recommendedName: Heat shock protein beta-1 shortName: HspB1 alternativeName: 28 kDa heat shock protein alternativeName: Estrogen-regulated 24 kDa protein alternativeName: Heat shock 27 kDa protein shortName: HSP 27 alternativeName: Heat shock protein family B member 1 alternativeName: Stress-responsive protein 27 shortName: SRP27
displayName	UniProt:P04792 HSPB1
geneName	HSPB1 HSP27 HSP28
identifier	P04792
isSequenceChanged	false
keyword	3D-structure Acetylation Chaperone Charcot-Marie-Tooth disease Cytoplasm Cytoskeleton Direct protein sequencing Disease variant Host-virus interaction Methylation Neurodegeneration Neuropathy Nucleus Phosphoprotein Proteomics identification Reference proteome Stress response
modified	[InstanceEdit:9963647] Weiser, Joel, 2025-08-15
moleculeType	Protein
name	HSPB1
otherIdentifier	11756054_x_at 17047504 17125292 17125294 201841_3p_s_at 201841_PM_s_at 201841_s_at 3009401 3009402 3009403 3009404 3009405 3009406 3009407 3009408 3009409 3009410 3009411 3009412 3009413 3009414 3009415 3209482 3315 36785_at 4008010 63673_at 8133721 A_14_P101807 A_23_P257704 A_24_P86537 A_33_P3353242 GE79739 GO:0000502 GO:0001533 GO:0001932 GO:0003723 GO:0005080 GO:0005515 GO:0005615 GO:0005634 GO:0005737 GO:0005819 GO:0005829 GO:0005856 GO:0005886 GO:0005925 GO:0006446 GO:0006457 GO:0006986 GO:0008426 GO:0009408 GO:0009615 GO:0010506 GO:0019901 GO:0030018 GO:0032731 GO:0032760 GO:0035556 GO:0035924 GO:0042026 GO:0042802 GO:0042803 GO:0043066 GO:0043122 GO:0043130 GO:0043226 GO:0043292 GO:0043536 GO:0044183 GO:0045766 GO:0048010 GO:0051082 GO:0061629 GO:0070062 GO:0070527 GO:0090038 GO:0098772 GO:0099641 GO:1902176 GO:1904115 GO:2001028 GO:2001234 HMNXSV003032430 ILMN_1674236 PH_hs_0028972 TC07000485.hg TC07000486.hg TC07002418.hg TC09002591.hg Z23090_at g4996892_3p_a_at g4996892_3p_x_at p26433
physicalEntity	[EntityWithAccessionedSequence:R-HSA-450563] HSPB1 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-5218697] p-S15,S78,S82-HSP27 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-5687009] p-S78,S82 HSPB1 [cytosol] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:ensembl:ENSG00000106211] ENSEMBL:ENSG00000106211 HSPB1 [ReferenceDNASequence:12671316] UCSC:P04792 HSPB1 [ReferenceDNASequence:12108413] OMIM:602195 HSPB1 [ReferenceDNASequence:12026699] NCBI Gene:3315 HSPB1 [ReferenceDNASequence:11942606] Monarch:3315 HSPB1 [ReferenceDNASequence:11856377] KEGG:hsa:3315 HSPB1 [ReferenceDNASequence:11816871] HGNC:5246 HSPB1 [ReferenceDNASequence:11426879] dbSNP Gene:3315 HSPB1 [ReferenceDNASequence:11409624] CTD Gene:3315 HSPB1 [ReferenceDNASequence:11391273] COSMIC - genes:HSPB1 HSPB1 [ReferenceDNASequence:11312817] BioGPS Gene:3315 HSPB1
referenceTranscript	[ReferenceRNASequence:12496795] RefSeq:NM_001540.5 HSPB1
schemaClass	ReferenceGeneProduct
secondaryIdentifier	HSPB1_HUMAN B2R4N8 Q6FI47 Q96C20 Q96EI7 Q9UC31 Q9UC34 Q9UC35 Q9UC36
sequenceLength	205
species	[Species:48887] Homo sapiens
stId	uniprot:P04792
url	http://purl.uniprot.org/uniprot/P04792

Referrals

(referenceEntity)	[EntityWithAccessionedSequence:R-HSA-450563] HSPB1 [cytosol] [EntityWithAccessionedSequence:R-HSA-5218697] p-S15,S78,S82-HSP27 [cytosol] [EntityWithAccessionedSequence:R-HSA-5687009] p-S78,S82 HSPB1 [cytosol]
(referenceSequence)	[ModifiedResidue:5218699] O-phospho-L-serine at 15 [ModifiedResidue:5218726] O-phospho-L-serine at 82 [ModifiedResidue:5218708] O-phospho-L-serine at 78
(interactor)	[UndirectedInteraction:11183159] UniProt:P04792 <-> UniProt:Q9UJY1 (IntAct) [UndirectedInteraction:11183157] UniProt:P04792 <-> UniProt:P55072 (IntAct) [UndirectedInteraction:11183155] UniProt:P04792 <-> UniProt:Q14240 (IntAct) [UndirectedInteraction:11183153] UniProt:P04792 <-> UniProt:O00273 (IntAct) [UndirectedInteraction:11183151] UniProt:P04792 <-> UniProt:Q7Z6Z7 (IntAct) [UndirectedInteraction:11183149] UniProt:P04792 <-> UniProt:P13693 (IntAct) [UndirectedInteraction:11183147] UniProt:P04792 <-> UniProt:P02794 (IntAct) [UndirectedInteraction:11183145] UniProt:P04792 <-> UniProt:Q9Y657 (IntAct) [UndirectedInteraction:11183143] UniProt:P04792 <-> UniProt:P13010 (IntAct) [UndirectedInteraction:11183141] UniProt:P04792 <-> UniProt:Q8N7H5 (IntAct) [UndirectedInteraction:11183139] UniProt:P04792 <-> UniProt:P78318 (IntAct) [UndirectedInteraction:11183135] UniProt:P04792 <-> UniProt:Q86YS6 (IntAct) [UndirectedInteraction:11183133] UniProt:P04792 <-> UniProt:Q96G03 (IntAct) [UndirectedInteraction:11183131] UniProt:P04792 <-> UniProt:P27797 (IntAct) [UndirectedInteraction:11183129] UniProt:P04792 <-> UniProt:Q15029 (IntAct) [UndirectedInteraction:11183127] UniProt:P04792 <-> UniProt:P78344 (IntAct) [UndirectedInteraction:11183125] UniProt:P04792 <-> UniProt:Q12874 (IntAct) [UndirectedInteraction:11183123] UniProt:P04792 <-> UniProt:O14558 (IntAct) [UndirectedInteraction:11183119] UniProt:P04792 <-> UniProt:P01106 (IntAct) [UndirectedInteraction:11183117] UniProt:P04792 <-> UniProt:P62993 (IntAct) [UndirectedInteraction:11183115] UniProt:P04792 <-> UniProt:P08473 (IntAct) [UndirectedInteraction:11183113] UniProt:P04792 <-> UniProt:P51114 (IntAct) [UndirectedInteraction:11183111] UniProt:P04792 <-> UniProt:P35813 (IntAct) [UndirectedInteraction:11183109] UniProt:P04792 <-> UniProt:Q8IUI8 (IntAct) [UndirectedInteraction:11183107] UniProt:P04792 <-> UniProt:Q96MN9-2 (IntAct) [UndirectedInteraction:11183103] UniProt:P04792 <-> UniProt:Q86V28 (IntAct) [UndirectedInteraction:11183101] UniProt:P04792 <-> UniProt:Q96K21 (IntAct) [UndirectedInteraction:11183097] UniProt:P04792 <-> UniProt:Q6PJW8-3 (IntAct) [UndirectedInteraction:11183095] UniProt:P04792 <-> UniProt:Q9NSD5-3 (IntAct) [UndirectedInteraction:11183091] UniProt:P04792 <-> UniProt:APLN (IntAct) [UndirectedInteraction:11183087] UniProt:P04792 <-> UniProt:Q9NTN9-3 (IntAct) [UndirectedInteraction:11183085] UniProt:P04792 <-> UniProt:Q6NTF9-3 (IntAct) [UndirectedInteraction:11183083] UniProt:P04792 <-> UniProt:Q8IZU1 (IntAct) [UndirectedInteraction:11183081] UniProt:P04792 <-> UniProt:Q96D59 (IntAct) [UndirectedInteraction:11183079] UniProt:P04792 <-> UniProt:P11908 (IntAct) [UndirectedInteraction:11183077] UniProt:P04792 <-> UniProt:Q6NXG1 (IntAct) [UndirectedInteraction:11183075] UniProt:P04792 <-> UniProt:Q86TN1 (IntAct) [UndirectedInteraction:11183073] UniProt:P04792 <-> UniProt:Q9Y5P3 (IntAct) [UndirectedInteraction:11183071] UniProt:P04792 <-> UniProt:Q8N8A2-2 (IntAct) [UndirectedInteraction:11183067] UniProt:P04792 <-> UniProt:Q99608 (IntAct) [UndirectedInteraction:11183065] UniProt:P04792 <-> UniProt:P62244 (IntAct) [UndirectedInteraction:11183063] UniProt:P04792 <-> IntAct:EBI-25859406 (IntAct) [UndirectedInteraction:11183059] UniProt:P04792 <-> UniProt:Q9H0W9-4 (IntAct) [UndirectedInteraction:11183055] UniProt:P04792 <-> UniProt:Q8N594 (IntAct) [UndirectedInteraction:11183053] UniProt:P04792 <-> UniProt:P58304 (IntAct) [UndirectedInteraction:11183049] UniProt:P04792 <-> UniProt:Q14847-2 (IntAct) [UndirectedInteraction:11183047] UniProt:P04792 <-> UniProt:P08195-4 (IntAct) [UndirectedInteraction:11183043] UniProt:P04792 <-> UniProt:P0C870 (IntAct) [UndirectedInteraction:11183041] UniProt:P04792 <-> UniProt:Q49AJ0-4 (IntAct) [UndirectedInteraction:11183039] UniProt:P04792 <-> UniProt:Q96LB9 (IntAct) [UndirectedInteraction:11183037] UniProt:P04792 <-> UniProt:Q6P587-2 (IntAct) [UndirectedInteraction:11183035] UniProt:P04792 <-> UniProt:Q96FW1 (IntAct) [UndirectedInteraction:11183033] UniProt:P04792 <-> UniProt:Q8N6K7-2 (IntAct) [UndirectedInteraction:11183031] UniProt:P04792 <-> UniProt:Q6UXG2-3 (IntAct) [UndirectedInteraction:11183027] UniProt:P04792 <-> UniProt:P08758 (IntAct) [UndirectedInteraction:11183025] UniProt:P04792 <-> UniProt:P57682 (IntAct) [UndirectedInteraction:11183023] UniProt:P04792 <-> UniProt:Q7L8T7 (IntAct) [UndirectedInteraction:11183019] UniProt:P04792 <-> UniProt:O00148 (IntAct) [UndirectedInteraction:11183017] UniProt:P04792 <-> UniProt:P36406 (IntAct) [UndirectedInteraction:11183015] UniProt:P04792 <-> UniProt:Q86WV8 (IntAct) [UndirectedInteraction:11183013] UniProt:P04792 <-> UniProt:Q86WV5 (IntAct) [UndirectedInteraction:11183011] UniProt:P04792 <-> UniProt:Q9NSI6-4 (IntAct) [UndirectedInteraction:11183009] UniProt:P04792 <-> UniProt:Q96LC9 (IntAct) [UndirectedInteraction:11183007] UniProt:P04792 <-> UniProt:Q9NXC2 (IntAct) [UndirectedInteraction:11183005] UniProt:P04792 <-> UniProt:Q14457 (IntAct) [UndirectedInteraction:11183003] UniProt:P04792 <-> IntAct:EBI-25840120 (IntAct) [UndirectedInteraction:11182999] UniProt:P04792 <-> UniProt:Q99932-2 (IntAct) [UndirectedInteraction:11182997] UniProt:P04792 <-> UniProt:Q92688 (IntAct) [UndirectedInteraction:11182993] UniProt:P04792 <-> UniProt:Q8NBM4-4 (IntAct) [UndirectedInteraction:11182989] UniProt:P04792 <-> UniProt:P51608 (IntAct) [UndirectedInteraction:11182987] UniProt:P04792 <-> IntAct:EBI-25836220 (IntAct) [UndirectedInteraction:11182985] UniProt:P04792 <-> UniProt:Q9Y2M5 (IntAct) [UndirectedInteraction:11182983] UniProt:P04792 <-> UniProt:A2RU56 (IntAct) [UndirectedInteraction:11182979] UniProt:P04792 <-> UniProt:Q96N77-2 (IntAct) [UndirectedInteraction:11182975] UniProt:P04792 <-> UniProt:Q5VWN6 (IntAct) [UndirectedInteraction:11182973] UniProt:P04792 <-> UniProt:A0A1B0GWI1 (IntAct) [UndirectedInteraction:11182971] UniProt:P04792 <-> UniProt:Q9BUF5 (IntAct) [UndirectedInteraction:11182969] UniProt:P04792 <-> UniProt:Q8NBJ7 (IntAct) [UndirectedInteraction:11182967] UniProt:P04792 <-> UniProt:Q969T4 (IntAct) [UndirectedInteraction:11182965] UniProt:P04792 <-> UniProt:Q9UKP3-2 (IntAct) [UndirectedInteraction:11182961] UniProt:P04792 <-> UniProt:Q8NBF2-2 (IntAct) [UndirectedInteraction:11182957] UniProt:P04792 <-> UniProt:Q9BS34 (IntAct) [UndirectedInteraction:11182955] UniProt:P04792 <-> UniProt:Q96FT7-4 (IntAct) [UndirectedInteraction:11182953] UniProt:P04792 <-> UniProt:Q66K80 (IntAct) [UndirectedInteraction:11182951] UniProt:P04792 <-> UniProt:P62979 (IntAct) [UndirectedInteraction:11182949] UniProt:P04792 <-> UniProt:Q96DZ5 (IntAct) [UndirectedInteraction:11182947] UniProt:P04792 <-> UniProt:Q16611 (IntAct) [UndirectedInteraction:11182945] UniProt:P04792 <-> UniProt:Q96GL9 (IntAct) [UndirectedInteraction:11182943] UniProt:P04792 <-> UniProt:Q99614 (IntAct) [UndirectedInteraction:11182941] UniProt:P04792 <-> UniProt:Q5TAQ9-2 (IntAct) [UndirectedInteraction:11182939] UniProt:P04792 <-> UniProt:O00757 (IntAct) [UndirectedInteraction:11182937] UniProt:P04792 <-> IntAct:EBI-25835277 (IntAct) [UndirectedInteraction:11182935] UniProt:P04792 <-> UniProt:Q9NP61 (IntAct) [UndirectedInteraction:11182933] UniProt:P04792 <-> UniProt:Q96A09 (IntAct) [UndirectedInteraction:11182931] UniProt:P04792 <-> UniProt:Q53NU3 (IntAct) [UndirectedInteraction:11182929] UniProt:P04792 <-> UniProt:Q8NA54 (IntAct) [UndirectedInteraction:11182927] UniProt:P04792 <-> UniProt:Q96SI1-2 (IntAct) [UndirectedInteraction:11182925] UniProt:P04792 <-> UniProt:Q9NZJ9 (IntAct) [UndirectedInteraction:11182923] UniProt:P04792 <-> UniProt:Q96JB6 (IntAct) [UndirectedInteraction:11182921] UniProt:P04792 <-> UniProt:A0A0A0MR05 (IntAct) [UndirectedInteraction:11182919] UniProt:P04792 <-> UniProt:Q6XD76 (IntAct) [UndirectedInteraction:11182917] UniProt:P04792 <-> IntAct:EBI-25831465 (IntAct) [UndirectedInteraction:11182913] UniProt:P04792 <-> UniProt:P05067 (IntAct) [UndirectedInteraction:11182911] UniProt:P04792 <-> UniProt:Q3SY46 (IntAct) [UndirectedInteraction:11182909] UniProt:P04792 <-> UniProt:O95872 (IntAct) [UndirectedInteraction:11182907] UniProt:P04792 <-> UniProt:Q7L591-3 (IntAct) [UndirectedInteraction:11182905] UniProt:P04792 <-> UniProt:Q8TBF4 (IntAct) [UndirectedInteraction:11182903] UniProt:P04792 <-> IntAct:EBI-25857950 (IntAct) [UndirectedInteraction:11182899] UniProt:P04792 <-> UniProt:Q17RD7-3 (IntAct) [UndirectedInteraction:11182895] UniProt:P04792 <-> UniProt:Q13569 (IntAct) [UndirectedInteraction:11182893] UniProt:P04792 <-> UniProt:O75925 (IntAct) [UndirectedInteraction:11182891] UniProt:P04792 <-> UniProt:Q9NXX0 (IntAct) [UndirectedInteraction:11182887] UniProt:P04792 <-> UniProt:Q8TC84 (IntAct) [UndirectedInteraction:11182883] UniProt:P04792 <-> UniProt:Q8IXS7 (IntAct) [UndirectedInteraction:11182879] UniProt:P04792 <-> UniProt:A0AVI4-2 (IntAct) [UndirectedInteraction:11182875] UniProt:P04792 <-> UniProt:Q2QGD7 (IntAct) [UndirectedInteraction:11182871] UniProt:P04792 <-> UniProt:P15313 (IntAct) [UndirectedInteraction:11182869] UniProt:P04792 <-> UniProt:Q58EX7-2 (IntAct) [UndirectedInteraction:11182867] UniProt:P04792 <-> UniProt:Q96LL4 (IntAct) [UndirectedInteraction:11182863] UniProt:P04792 <-> UniProt:Q8IYI0 (IntAct) [UndirectedInteraction:11182861] UniProt:P04792 <-> UniProt:B7Z3E8 (IntAct) [UndirectedInteraction:11182859] UniProt:P04792 <-> UniProt:Q5BJF6-2 (IntAct) [UndirectedInteraction:11182857] UniProt:P04792 <-> UniProt:O94778 (IntAct) [UndirectedInteraction:11182855] UniProt:P04792 <-> UniProt:P45880 (IntAct) [UndirectedInteraction:11182853] UniProt:P04792 <-> UniProt:Q6ZU52 (IntAct) [UndirectedInteraction:11182851] UniProt:P04792 <-> IntAct:EBI-25870739 (IntAct) [UndirectedInteraction:11182847] UniProt:P04792 <-> UniProt:Q8TDP1 (IntAct) [UndirectedInteraction:11182843] UniProt:P04792 <-> UniProt:Q8WZ19 (IntAct) [UndirectedInteraction:11182841] UniProt:P04792 <-> UniProt:Q3SYF9 (IntAct) [UndirectedInteraction:11182839] UniProt:P04792 <-> UniProt:P01040 (IntAct) [UndirectedInteraction:11182837] UniProt:P04792 <-> UniProt:Q8WUY3 (IntAct) [UndirectedInteraction:11182835] UniProt:P04792 <-> UniProt:Q8N6F8 (IntAct) [UndirectedInteraction:11182833] UniProt:P04792 <-> UniProt:Q9Y3D0 (IntAct) [UndirectedInteraction:11182831] UniProt:P04792 <-> UniProt:P28062-2 (IntAct) [UndirectedInteraction:11182829] UniProt:P04792 <-> UniProt:O43741 (IntAct) [UndirectedInteraction:11182827] UniProt:P04792 <-> UniProt:Q6UY14-3 (IntAct) [UndirectedInteraction:11182825] UniProt:P04792 <-> UniProt:P21980-2 (IntAct) [UndirectedInteraction:11182821] UniProt:P04792 <-> UniProt:P13928 (IntAct) [UndirectedInteraction:11182817] UniProt:P04792 <-> UniProt:P46379-2 (IntAct) [UndirectedInteraction:11182815] UniProt:P04792 <-> UniProt:Q15049 (IntAct) [UndirectedInteraction:11182811] UniProt:P04792 <-> UniProt:Q8N5U6 (IntAct) [UndirectedInteraction:11182809] UniProt:P04792 <-> UniProt:Q6P1L5 (IntAct) [UndirectedInteraction:11182807] UniProt:P04792 <-> UniProt:Q14995 (IntAct) [UndirectedInteraction:11182805] UniProt:P04792 <-> IntAct:EBI-25839678 (IntAct) [UndirectedInteraction:11182801] UniProt:P04792 <-> UniProt:Q9UIH9 (IntAct) [UndirectedInteraction:11182799] UniProt:P04792 <-> UniProt:Q9Y3Q8 (IntAct) [UndirectedInteraction:11182797] UniProt:P04792 <-> UniProt:Q6ZTN6-2 (IntAct) [UndirectedInteraction:11182795] UniProt:P04792 <-> IntAct:EBI-25849442 (IntAct) [UndirectedInteraction:11182793] UniProt:P04792 <-> UniProt:Q8NDP9 (IntAct) [UndirectedInteraction:11182789] UniProt:P04792 <-> IntAct:EBI-25835866 (IntAct) [UndirectedInteraction:11182787] UniProt:P04792 <-> UniProt:Q9H9Q2 (IntAct) [UndirectedInteraction:11182785] UniProt:P04792 <-> UniProt:Q8N5S9-2 (IntAct) [UndirectedInteraction:11182783] UniProt:P04792 <-> UniProt:O00303 (IntAct) [UndirectedInteraction:11182781] UniProt:P04792 <-> UniProt:Q8IUR5-4 (IntAct) [UndirectedInteraction:11182777] UniProt:P04792 <-> UniProt:Q8NA72-3 (IntAct) [UndirectedInteraction:11182773] UniProt:P04792 <-> IntAct:EBI-25836274 (IntAct) [UndirectedInteraction:11182771] UniProt:P04792 <-> UniProt:O75604-3 (IntAct) [UndirectedInteraction:11182769] UniProt:P04792 <-> UniProt:Q9UNS2 (IntAct) [UndirectedInteraction:11182767] UniProt:P04792 <-> UniProt:Q9BQA1 (IntAct) [UndirectedInteraction:11182765] UniProt:P04792 <-> UniProt:Q9NVX7-2 (IntAct) [UndirectedInteraction:11182761] UniProt:P04792 <-> UniProt:Q03112-9 (IntAct) [UndirectedInteraction:11182757] UniProt:P04792 <-> UniProt:P15976-2 (IntAct) [UndirectedInteraction:11182755] UniProt:P04792 <-> UniProt:Q9BPU6 (IntAct) [UndirectedInteraction:11182753] UniProt:P04792 <-> UniProt:Q9UF11-2 (IntAct) [UndirectedInteraction:11182749] UniProt:P04792 <-> IntAct:EBI-25835770 (IntAct) [UndirectedInteraction:11182747] UniProt:P04792 <-> UniProt:O15381-5 (IntAct) [UndirectedInteraction:11182745] UniProt:P04792 <-> UniProt:Q6RVD6 (IntAct) [UndirectedInteraction:11182743] UniProt:P04792 <-> UniProt:P36639-4 (IntAct) [UndirectedInteraction:11182741] UniProt:P04792 <-> UniProt:Q6ZR37 (IntAct) [UndirectedInteraction:11182739] UniProt:P04792 <-> UniProt:Q92966 (IntAct) [UndirectedInteraction:11182737] UniProt:P04792 <-> UniProt:O60830 (IntAct) [UndirectedInteraction:11182735] UniProt:P04792 <-> UniProt:Q8IYN2 (IntAct) [UndirectedInteraction:11182731] UniProt:P04792 <-> UniProt:Q71RG4-4 (IntAct) [UndirectedInteraction:11182727] UniProt:P04792 <-> UniProt:Q9UDY8-2 (IntAct) [UndirectedInteraction:11182725] UniProt:P04792 <-> UniProt:Q04323-2 (IntAct) [UndirectedInteraction:11182721] UniProt:P04792 <-> UniProt:Q8WVN8 (IntAct) [UndirectedInteraction:11182719] UniProt:P04792 <-> UniProt:A0A384ME25 (IntAct) [UndirectedInteraction:11182715] UniProt:P04792 <-> IntAct:EBI-25861384 (IntAct) [UndirectedInteraction:11182711] UniProt:P04792 <-> UniProt:Q9UPM6 (IntAct) [UndirectedInteraction:11182709] UniProt:P04792 <-> UniProt:Q8N1A0 (IntAct) [UndirectedInteraction:11182707] UniProt:P04792 <-> UniProt:Q9HC96 (IntAct) [UndirectedInteraction:11182705] UniProt:P04792 <-> UniProt:Q8TCT7-2 (IntAct) [UndirectedInteraction:11182701] UniProt:P04792 <-> UniProt:Q17RN3 (IntAct) [UndirectedInteraction:11182697] UniProt:P04792 <-> UniProt:Q16670 (IntAct) [UndirectedInteraction:11182693] UniProt:P04792 <-> UniProt:Q8IUC2 (IntAct) [UndirectedInteraction:11182691] UniProt:P04792 <-> UniProt:Q8N5V2 (IntAct) [UndirectedInteraction:11182689] UniProt:P04792 <-> IntAct:EBI-25831516 (IntAct) [UndirectedInteraction:11182685] UniProt:P04792 <-> UniProt:Q96PV6 (IntAct) [UndirectedInteraction:11182683] UniProt:P04792 <-> IntAct:EBI-25835796 (IntAct) [UndirectedInteraction:11182681] UniProt:P04792 <-> UniProt:O77932 (IntAct) [UndirectedInteraction:11182679] UniProt:P04792 <-> UniProt:Q9NZC7-5 (IntAct) [UndirectedInteraction:11182675] UniProt:P04792 <-> UniProt:Q9C004 (IntAct) [UndirectedInteraction:11182673] UniProt:P04792 <-> UniProt:O15287 (IntAct) [UndirectedInteraction:11182671] UniProt:P04792 <-> UniProt:Q5VYS8-5 (IntAct) [UndirectedInteraction:11182669] UniProt:P04792 <-> UniProt:Q9Y575-3 (IntAct) [UndirectedInteraction:11182667] UniProt:P04792 <-> IntAct:EBI-25848398 (IntAct) [UndirectedInteraction:11182663] UniProt:P04792 <-> UniProt:Q14005-2 (IntAct) [UndirectedInteraction:11182661] UniProt:P04792 <-> IntAct:EBI-25843264 (IntAct) [UndirectedInteraction:11182659] UniProt:P04792 <-> UniProt:Q6GQQ9-2 (IntAct) [UndirectedInteraction:11182657] UniProt:P04792 <-> UniProt:P61244-4 (IntAct) [UndirectedInteraction:11133147] UniProt:Q99683 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11142119] UniProt:Q13573 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11144149] UniProt:Q96FX8 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11146507] UniProt:Q02790 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11146571] UniProt:P78417 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11147723] UniProt:P13569 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11151075] UniProt:Q06136 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11152525] UniProt:P31749 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11155135] UniProt:P47897 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11155879] UniProt:Q14693 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11160375] UniProt:P48431 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11162601] UniProt:P08865 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11163097] UniProt:O15534 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11166961] UniProt:P62333 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11169627] UniProt:Q9UER7 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11182595] UniProt:P04792 <-> UniProt:P02511 (IntAct) [UndirectedInteraction:11182597] UniProt:P04792 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11182597] UniProt:P04792 <-> UniProt:P04792 (IntAct) [UndirectedInteraction:11182599] UniProt:P04792 <-> UniProt:O95817 (IntAct) [UndirectedInteraction:11182601] UniProt:P04792 <-> UniProt:P02489 (IntAct) [UndirectedInteraction:11182603] UniProt:P04792 <-> UniProt:P63104 (IntAct) [UndirectedInteraction:11182605] UniProt:P04792 <-> UniProt:Q9BRX9 (IntAct) [UndirectedInteraction:11182607] UniProt:P04792 <-> UniProt:Q9BRX2 (IntAct) [UndirectedInteraction:11182609] UniProt:P04792 <-> UniProt:Q9UNE7 (IntAct) [UndirectedInteraction:11182611] UniProt:P04792 <-> UniProt:P04637 (IntAct) [UndirectedInteraction:11182613] UniProt:P04792 <-> UniProt:P00533 (IntAct) [UndirectedInteraction:11182617] UniProt:P04792 <-> UniProt:Q9HBQ8 (IntAct) [UndirectedInteraction:11182621] UniProt:P04792 <-> UniProt:P02602 (IntAct) [UndirectedInteraction:11182625] UniProt:P04792 <-> UniProt:P02562 (IntAct) [UndirectedInteraction:11182627] UniProt:P04792 <-> UniProt:P49137 (IntAct) [UndirectedInteraction:11182629] UniProt:P04792 <-> UniProt:Q16644 (IntAct) [UndirectedInteraction:11182631] UniProt:P04792 <-> UniProt:Q13418 (IntAct) [UndirectedInteraction:11182633] UniProt:P04792 <-> UniProt:Q8N448 (IntAct) [UndirectedInteraction:11182635] UniProt:P04792 <-> UniProt:Q9H1D9 (IntAct) [UndirectedInteraction:11182639] UniProt:P04792 <-> UniProt:Q9NUL5-3 (IntAct) [UndirectedInteraction:11182641] UniProt:P04792 <-> UniProt:Q96EW2-2 (IntAct) [UndirectedInteraction:11182643] UniProt:P04792 <-> UniProt:Q9Y4H4 (IntAct) [UndirectedInteraction:11182647] UniProt:P04792 <-> IntAct:EBI-25851697 (IntAct) [UndirectedInteraction:11182651] UniProt:P04792 <-> UniProt:hCG_41307 (IntAct) [UndirectedInteraction:11182653] UniProt:P04792 <-> UniProt:Q7Z602 (IntAct)

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