Reactome | UniProt:P04050

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UniProt:P04050 Show undefined attributes

created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
crossReference	[DatabaseIdentifier:11484311] ENSEMBL:YDL140C [DatabaseIdentifier:12394152] RefSeq:NP_010141.1 [DatabaseIdentifier:12277985] PRO:P04050 [DatabaseIdentifier:12149405] PDB:6GYL [DatabaseIdentifier:12149384] PDB:1NT9 [DatabaseIdentifier:12145631] PDB:8UOQ [DatabaseIdentifier:12149380] PDB:7RIY [DatabaseIdentifier:12145619] PDB:7O73 [DatabaseIdentifier:12149423] PDB:3GTL [DatabaseIdentifier:12149426] PDB:6BQF [DatabaseIdentifier:12233996] PDB:5M9D [DatabaseIdentifier:12149397] PDB:4A3B [DatabaseIdentifier:12145624] PDB:7O4K [DatabaseIdentifier:12149419] PDB:3RZO [DatabaseIdentifier:12149364] PDB:7RIM [DatabaseIdentifier:12149409] PDB:4A3G [DatabaseIdentifier:12149417] PDB:3GTP [DatabaseIdentifier:12145614] PDB:7O72 [DatabaseIdentifier:12149375] PDB:8UKS [DatabaseIdentifier:12149394] PDB:3I4M [DatabaseIdentifier:12149369] PDB:6BM4 [DatabaseIdentifier:12149361] PDB:6UPX [DatabaseIdentifier:12149363] PDB:3QT1 [DatabaseIdentifier:12149396] PDB:5C4A [DatabaseIdentifier:12149421] PDB:3GTJ [DatabaseIdentifier:12149387] PDB:3K7A [DatabaseIdentifier:12149415] PDB:4A3M [DatabaseIdentifier:12149365] PDB:4BBR [DatabaseIdentifier:12210229] PDB:2L0I [DatabaseIdentifier:12145616] PDB:7O4L [DatabaseIdentifier:12145618] PDB:7O75 [DatabaseIdentifier:12149398] PDB:4A3C [DatabaseIdentifier:12149382] PDB:2B8K [DatabaseIdentifier:12149399] PDB:4A3D [DatabaseIdentifier:12149404] PDB:6GYK [DatabaseIdentifier:12149395] PDB:3H3V [DatabaseIdentifier:12149390] PDB:5IP9 [DatabaseIdentifier:12149388] PDB:6O6C [DatabaseIdentifier:12149392] PDB:5FZ5 [DatabaseIdentifier:12149430] PDB:3GTG [DatabaseIdentifier:12149411] PDB:4A3J [DatabaseIdentifier:12149374] PDB:8UKR [DatabaseIdentifier:12149407] PDB:5C4X [DatabaseIdentifier:12191155] PDB:5VKO [DatabaseIdentifier:12149400] PDB:4A3E [DatabaseIdentifier:12149378] PDB:2R92 [DatabaseIdentifier:12149373] PDB:8UKU [DatabaseIdentifier:12233995] PDB:5LVF [DatabaseIdentifier:12149429] PDB:2E2H [DatabaseIdentifier:12149427] PDB:2E2J [DatabaseIdentifier:12149410] PDB:4A3I [DatabaseIdentifier:12145626] PDB:7O4I [DatabaseIdentifier:12149358] PDB:3HOZ [DatabaseIdentifier:12149368] PDB:6BLP [DatabaseIdentifier:12149379] PDB:7RIX [DatabaseIdentifier:12149422] PDB:3GTK [DatabaseIdentifier:12149381] PDB:7RIW [DatabaseIdentifier:12149372] PDB:8UKT [DatabaseIdentifier:12145627] PDB:8UOT [DatabaseIdentifier:12149408] PDB:4A3F [DatabaseIdentifier:12149366] PDB:4BBS [DatabaseIdentifier:12149386] PDB:7RIQ [DatabaseIdentifier:12149359] PDB:6UQ3 [DatabaseIdentifier:12149428] PDB:2E2I [DatabaseIdentifier:12149377] PDB:2R93 [DatabaseIdentifier:12149362] PDB:1Y77 [DatabaseIdentifier:12145629] PDB:8UMH [DatabaseIdentifier:12149406] PDB:9BVT [DatabaseIdentifier:12145623] PDB:7O4J [DatabaseIdentifier:12149413] PDB:5C4J [DatabaseIdentifier:12149416] PDB:2VUM [DatabaseIdentifier:12145636] PDB:6GYM [DatabaseIdentifier:12149412] PDB:4A3K [DatabaseIdentifier:12149401] PDB:5C44 [DatabaseIdentifier:12149403] PDB:5C3E [DatabaseIdentifier:12143800] PDB:2LO6 [DatabaseIdentifier:12149383] PDB:2R7Z [DatabaseIdentifier:12149391] PDB:3I4N [DatabaseIdentifier:12149370] PDB:6BLO [DatabaseIdentifier:12149424] PDB:3GTM [DatabaseIdentifier:12149402] PDB:9BW0 [DatabaseIdentifier:12149385] PDB:7RIP [DatabaseIdentifier:12149371] PDB:8UKQ [DatabaseIdentifier:12149418] PDB:3GTQ [DatabaseIdentifier:12149360] PDB:6UQ2 [DatabaseIdentifier:12191152] PDB:5VKL [DatabaseIdentifier:12149376] PDB:5U5Q [DatabaseIdentifier:12149393] PDB:5FYW [DatabaseIdentifier:12149420] PDB:3RZD [DatabaseIdentifier:12145635] PDB:5SVA [DatabaseIdentifier:12149414] PDB:4A3L [DatabaseIdentifier:12145630] PDB:8UMI [DatabaseIdentifier:12149357] PDB:2YU9 [DatabaseIdentifier:12149367] PDB:6BM2 [DatabaseIdentifier:12149425] PDB:3GTO [DatabaseIdentifier:12149389] PDB:5IP7 [DatabaseIdentifier:12149290] PDB:3M4O [DatabaseIdentifier:12149348] PDB:2B63 [DatabaseIdentifier:12149281] PDB:2JA6 [DatabaseIdentifier:12149311] PDB:9N5F [DatabaseIdentifier:12149286] PDB:5OT2 [DatabaseIdentifier:12149280] PDB:2JA7 [DatabaseIdentifier:12149321] PDB:5W51 [DatabaseIdentifier:12145622] PDB:7ZS9 [DatabaseIdentifier:12149302] PDB:1PQV [DatabaseIdentifier:12140074] PDB:8RAP [DatabaseIdentifier:12149356] PDB:6UPY [DatabaseIdentifier:12149291] PDB:7KEE [DatabaseIdentifier:12149325] PDB:8TVP [DatabaseIdentifier:12149301] PDB:3S1N [DatabaseIdentifier:12149333] PDB:3J1N [DatabaseIdentifier:12149319] PDB:8TVX [DatabaseIdentifier:12149355] PDB:6UPZ [DatabaseIdentifier:12149312] PDB:3S17 [DatabaseIdentifier:12149294] PDB:3M3Y [DatabaseIdentifier:12149327] PDB:3S2H [DatabaseIdentifier:12149317] PDB:8TVS [DatabaseIdentifier:12149351] PDB:1WCM [DatabaseIdentifier:12149346] PDB:3PO2 [DatabaseIdentifier:12149310] PDB:3S16 [DatabaseIdentifier:12149315] PDB:7NKY [DatabaseIdentifier:12149308] PDB:3S15 [DatabaseIdentifier:12149295] PDB:1Y1W [DatabaseIdentifier:12149340] PDB:6UQ1 [DatabaseIdentifier:12149282] PDB:2JA5 [DatabaseIdentifier:12149292] PDB:7KEF [DatabaseIdentifier:12149332] PDB:7MK9 [DatabaseIdentifier:12149289] PDB:7KED [DatabaseIdentifier:12149288] PDB:1Y1Y [DatabaseIdentifier:12149354] PDB:1R9S [DatabaseIdentifier:12222626] PDB:8U9R [DatabaseIdentifier:12143834] PDB:7UIO [DatabaseIdentifier:12149334] PDB:8JCH [DatabaseIdentifier:12145611] PDB:7ML2 [DatabaseIdentifier:12149309] PDB:9N5G [DatabaseIdentifier:12140080] PDB:8RAM [DatabaseIdentifier:12149320] PDB:8TVV [DatabaseIdentifier:12149323] PDB:3J0K [DatabaseIdentifier:12149316] PDB:9N5D [DatabaseIdentifier:12145606] PDB:7ML0 [DatabaseIdentifier:12149318] PDB:1I50 [DatabaseIdentifier:12143817] PDB:8TVY [DatabaseIdentifier:12149314] PDB:9N5E [DatabaseIdentifier:12149279] PDB:4V1O [DatabaseIdentifier:12149336] PDB:3HOU [DatabaseIdentifier:12149277] PDB:4X6A [DatabaseIdentifier:12149304] PDB:3K1F [DatabaseIdentifier:12149353] PDB:1R9T [DatabaseIdentifier:12149328] PDB:1R5U [DatabaseIdentifier:12149296] PDB:1Y1V [DatabaseIdentifier:12149278] PDB:2JA8 [DatabaseIdentifier:12149306] PDB:9N5B [DatabaseIdentifier:12149339] PDB:3HOX [DatabaseIdentifier:12149337] PDB:3HOV [DatabaseIdentifier:12149303] PDB:8TUG [DatabaseIdentifier:12145634] PDB:8CEO [DatabaseIdentifier:12149349] PDB:9JA1 [DatabaseIdentifier:12149345] PDB:6I84 [DatabaseIdentifier:12149330] PDB:3S1Q [DatabaseIdentifier:12149287] PDB:7UIF [DatabaseIdentifier:12149284] PDB:4A93 [DatabaseIdentifier:12149293] PDB:7UI9 [DatabaseIdentifier:12149305] PDB:9N5C [DatabaseIdentifier:12149343] PDB:3FKI [DatabaseIdentifier:12149322] PDB:8TVW [DatabaseIdentifier:12149298] PDB:1I3Q [DatabaseIdentifier:12149299] PDB:1K83 [DatabaseIdentifier:12149285] PDB:3CQZ [DatabaseIdentifier:12222625] PDB:8U9X [DatabaseIdentifier:12145607] PDB:7ML1 [DatabaseIdentifier:12149352] PDB:5VVS [DatabaseIdentifier:12149276] PDB:1TWA [DatabaseIdentifier:12149324] PDB:3S2D [DatabaseIdentifier:12149329] PDB:7MKA [DatabaseIdentifier:12168265] PDB:6NPW [DatabaseIdentifier:12149297] PDB:1SFO [DatabaseIdentifier:12149326] PDB:8TVQ [DatabaseIdentifier:12149313] PDB:7NKX [DatabaseIdentifier:12158652] PDB:4GWQ [DatabaseIdentifier:12149300] PDB:3S1M [DatabaseIdentifier:12145613] PDB:7ZSB [DatabaseIdentifier:12149344] PDB:8K5P [DatabaseIdentifier:12149350] PDB:1I6H [DatabaseIdentifier:12149283] PDB:4X67 [DatabaseIdentifier:12149335] PDB:5W4U [DatabaseIdentifier:12158649] PDB:7UIG [DatabaseIdentifier:12149307] PDB:3S14 [DatabaseIdentifier:12145632] PDB:8CEN [DatabaseIdentifier:12149338] PDB:3HOW [DatabaseIdentifier:12149342] PDB:6UQ0 [DatabaseIdentifier:12149341] PDB:3HOY [DatabaseIdentifier:12145610] PDB:7ML4 [DatabaseIdentifier:12145617] PDB:7ZSA [DatabaseIdentifier:12143816] PDB:5VVR [DatabaseIdentifier:12149347] PDB:3PO3 [DatabaseIdentifier:12149331] PDB:3S1R [DatabaseIdentifier:12149263] PDB:2NVT [DatabaseIdentifier:12149267] PDB:4BY1 [DatabaseIdentifier:12149274] PDB:4V1N [DatabaseIdentifier:12149273] PDB:4V1M [DatabaseIdentifier:12149258] PDB:7MEI [DatabaseIdentifier:12149264] PDB:4BY7 [DatabaseIdentifier:12149275] PDB:1TWC [DatabaseIdentifier:12149271] PDB:4Y7N [DatabaseIdentifier:12149262] PDB:2NVX [DatabaseIdentifier:12149259] PDB:1NIK [DatabaseIdentifier:12149268] PDB:2NVZ [DatabaseIdentifier:12149266] PDB:4Y52 [DatabaseIdentifier:12149269] PDB:1TWH [DatabaseIdentifier:12145615] PDB:5OQJ [DatabaseIdentifier:12149272] PDB:1TWF [DatabaseIdentifier:12149257] PDB:2NVQ [DatabaseIdentifier:12149270] PDB:1TWG [DatabaseIdentifier:12145620] PDB:5OQM [DatabaseIdentifier:12145621] PDB:5FMF [DatabaseIdentifier:12149260] PDB:2NVY [DatabaseIdentifier:12149261] PDB:4BXZ [DatabaseIdentifier:12149265] PDB:4BXX [DatabaseIdentifier:11586798] ENSEMBL:YDL140C [DatabaseIdentifier:11709497] ENSEMBL:YDL140C_mRNA [DatabaseIdentifier:11850431] IntEnz:2.7.7.6
databaseName	UniProt
dbId	11081960
displayName	UniProt:P04050
identifier	P04050
moleculeType	Protein
otherIdentifier	851415 GO:0000428 GO:0001172 GO:0003674 GO:0003677 GO:0003899 GO:0003968 GO:0005515 GO:0005575 GO:0005634 GO:0005665 GO:0005739 GO:0006281 GO:0006351 GO:0006352 GO:0006354 GO:0006366 GO:0006367 GO:0006368 GO:0008270 GO:0010494 GO:0016740 GO:0016779 GO:0019985 GO:0034062 GO:0042789 GO:0043167 GO:0046872
physicalEntity	[EntityWithAccessionedSequence:R-SCE-63502] POLR2A [nucleoplasm] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-77100] phospho-p-S5(CTD)-POLR2A [nucleoplasm] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-113420] phospho-p-S2,S5(CTD)-POLR2A [nucleoplasm] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-6797701] phospho-p-3S-POLR2A [nucleoplasm] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-6781855] phospho-Ub,p-S2,S5(CTD)-POLR2A [nucleoplasm] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-6810226] phospho-p-S5,S7(CTD)-POLR2A [nucleoplasm] - Saccharomyces cerevisiae
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:11979385] Monarch:851415 [ReferenceDNASequence:12695266] UCSC:P04050 [ReferenceDNASequence:12063478] NCBI Gene:851415 [ReferenceDNASequence:ensembl.fungi:YDL140C] ENSEMBL:YDL140C [ReferenceDNASequence:11349596] BioGPS Gene:851415 [ReferenceDNASequence:11889466] KEGG:sce:YDL140C [ReferenceDNASequence:sgd:YDL140C] SGD:YDL140C
referenceTranscript	[ReferenceRNASequence:12575919] RefSeq:NM_001180200.1
schemaClass	ReferenceGeneProduct
species	[Species:68322] Saccharomyces cerevisiae
stId	uniprot:P04050
url	http://purl.uniprot.org/uniprot/P04050

Referrals

(referenceEntity)	[EntityWithAccessionedSequence:R-SCE-63502] POLR2A [nucleoplasm] [EntityWithAccessionedSequence:R-SCE-77100] phospho-p-S5(CTD)-POLR2A [nucleoplasm] [EntityWithAccessionedSequence:R-SCE-113420] phospho-p-S2,S5(CTD)-POLR2A [nucleoplasm] [EntityWithAccessionedSequence:R-SCE-6797701] phospho-p-3S-POLR2A [nucleoplasm] [EntityWithAccessionedSequence:R-SCE-6781855] phospho-Ub,p-S2,S5(CTD)-POLR2A [nucleoplasm] [EntityWithAccessionedSequence:R-SCE-6810226] phospho-p-S5,S7(CTD)-POLR2A [nucleoplasm]
(referenceSequence)	[ModifiedResidue:11081961] O-phospho-L-serine at 1843 (in Homo sapiens) [ModifiedResidue:11081963] O-phospho-L-serine at 1857 (in Homo sapiens) [ModifiedResidue:11081962] O-phospho-L-serine at 1850 (in Homo sapiens) [ModifiedResidue:11081965] O-phospho-L-serine at 1871 (in Homo sapiens) [ModifiedResidue:11081964] O-phospho-L-serine at 1864 (in Homo sapiens) [ModifiedResidue:11081967] O-phospho-L-serine at 1892 (in Homo sapiens) [ModifiedResidue:11081966] O-phospho-L-serine at 1878 (in Homo sapiens) [ModifiedResidue:11081969] O-phospho-L-serine at 1906 (in Homo sapiens) [ModifiedResidue:11081968] O-phospho-L-serine at 1899 (in Homo sapiens) [ModifiedResidue:11081971] O-phospho-L-serine at 1920 (in Homo sapiens) [ModifiedResidue:11081970] O-phospho-L-serine at 1913 (in Homo sapiens) [ModifiedResidue:11081973] O-phospho-L-serine at 1934 (in Homo sapiens) [ModifiedResidue:11081972] O-phospho-L-serine at 1927 (in Homo sapiens) [ModifiedResidue:11082056] O-phospho-L-serine at 1931 (in Homo sapiens) [ModifiedResidue:11082049] O-phospho-L-serine at 1875 (in Homo sapiens) [ModifiedResidue:11082048] O-phospho-L-serine at 1868 (in Homo sapiens) [ModifiedResidue:11082051] O-phospho-L-serine at 1889 (in Homo sapiens) [ModifiedResidue:11082050] O-phospho-L-serine at 1882 (in Homo sapiens) [ModifiedResidue:11082053] O-phospho-L-serine at 1910 (in Homo sapiens) [ModifiedResidue:11082052] O-phospho-L-serine at 1896 (in Homo sapiens) [ModifiedResidue:11082055] O-phospho-L-serine at 1924 (in Homo sapiens) [ModifiedResidue:11082054] O-phospho-L-serine at 1917 (in Homo sapiens) [ModifiedResidue:11082047] O-phospho-L-serine at 1861 (in Homo sapiens) [ModifiedResidue:11082046] O-phospho-L-serine at 1847 (in Homo sapiens) [ModifiedResidue:11098821] O-phospho-L-serine at unknown position [ModifiedResidue:11097768] ubiquitinylated lysine at unknown position [ModifiedResidue:11100968] O-phospho-L-serine at 1845 (in Homo sapiens)
(interactor)	[UndirectedInteraction:11136201] UniProt:P40084 <-> UniProt:P04050 (IntAct) [UndirectedInteraction:11187271] UniProt:P27692 <-> UniProt:P04050 (IntAct) [UndirectedInteraction:11228199] UniProt:P22696 <-> UniProt:P04050 (IntAct) [UndirectedInteraction:11237953] UniProt:P32914 <-> UniProt:P04050 (IntAct) [UndirectedInteraction:11289411] UniProt:P02309 <-> UniProt:P04050 (IntAct) [UndirectedInteraction:11292787] UniProt:Q05543 <-> UniProt:P04050 (IntAct)

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