Reactome | UniProt:P01893 HLA-H

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UniProt:P01893 HLA-H Show undefined attributes

chain	signal peptide:1-24 chain:25-362
checksum	8ADFD2388FEC4645
comment	FUNCTION Involved in the presentation of foreign antigens to the immune system.SUBUNIT Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin).INTERACTION Belongs to the MHC class I family.CAUTION Could be the product of a pseudogene.SEQUENCE CAUTION Truncated N-terminus.
crossReference	[DatabaseIdentifier:12285686] Pharos - Targets:P01893 [DatabaseIdentifier:12265060] PRO:P01893 [DatabaseIdentifier:12125402] OpenTargets:ENSG00000206341 [DatabaseIdentifier:11803281] GlyGen:P01893 [DatabaseIdentifier:11787786] GeneCards:HLA-H
databaseName	UniProt
dbId	56558
description	recommendedName: Putative HLA class I histocompatibility antigen, alpha chain H alternativeName: HLA-12.4 alternativeName: HLA-AR alternativeName: MHC class I antigen H
displayName	UniProt:P01893 HLA-H
geneName	HLA-H HLAH
identifier	P01893
isSequenceChanged	false
keyword	Cell membrane Disulfide bond Glycoprotein Immunity Membrane MHC I Proteomics identification Reference proteome Signal Transmembrane Transmembrane helix
modified	[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType	Protein
name	HLA-H
physicalEntity	[EntityWithAccessionedSequence:R-HSA-8855898] HLA-H [early endosome membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-8863855] HLA-H [recycling endosome membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-8855901] HLA-H [phagocytic vesicle membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-8855895] HLA-H [Golgi membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-8855892] HLA-H [ER to Golgi transport vesicle membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-6806266] HLA-H [plasma membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-6799339] HLA-H [azurophil granule membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-8855907] HLA-H [lumenal side of endoplasmic reticulum membrane] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:12764458] UCSC:P01893 HLA-H [ReferenceDNASequence:12107147] OMIM:142800 HLA-A [ReferenceDNASequence:11819432] HGNC:4965 HLA-H
schemaClass	ReferenceGeneProduct
secondaryIdentifier	HLAH_HUMAN
sequenceLength	362
species	[Species:48887] Homo sapiens
stId	uniprot:P01893
url	http://purl.uniprot.org/uniprot/P01893

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[UndirectedInteraction:11247097] UniProt:P11142 <-> UniProt:P01893 (IntAct)

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