UniProt:P01325 Ins1

chain
  • signal peptide:1-24
  • peptide:25-54
  • propeptide:57-85
  • peptide:88-108
checksum F63D9B7B896E0F88
comment
  • FUNCTION Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.SUBUNIT Heterodimer of a B chain and an A chain linked by two disulfide bonds.SUBCELLULAR LOCATION Belongs to the insulin family.
created [InstanceEdit:187302] Tello-Ruiz, MK, 2006-09-13 01:14:23
crossReference
databaseName UniProt
dbId 187280
description
  • recommendedName: Insulin-1 component recommendedName: Insulin-1 B chain /component component recommendedName: Insulin-1 A chain /component
displayName UniProt:P01325 Ins1
geneName
  • Ins1
  • Ins-1
identifier P01325
isSequenceChanged false
keyword
  • 3D-structure
  • Carbohydrate metabolism
  • Cleavage on pair of basic residues
  • Direct protein sequencing
  • Disulfide bond
  • Glucose metabolism
  • Hormone
  • Reference proteome
  • Secreted
  • Signal
modified [InstanceEdit:9852000] Weiser, Joel, 2023-11-03
moleculeType Protein
name
  • Ins1
otherIdentifier
  • 10463906
  • 1422447_at
  • 16333
  • 165489_f_at
  • 17360301
  • 4432096
  • 4631506
  • 5097014
  • 5434024
  • 97658_f_at
  • 97659_r_at
  • A_51_P312755
  • A_55_P1959318
  • GE118032
  • GO:0005158
  • GO:0005179
  • GO:0005576
  • GO:0005615
  • GO:0005788
  • GO:0005829
  • GO:0005975
  • GO:0006006
  • GO:0008286
  • GO:0016192
  • GO:0030297
  • GO:0030312
  • GO:0031012
  • GO:0031623
  • GO:0034097
  • GO:0034774
  • GO:0042593
  • GO:0043434
  • GO:0048018
  • GO:0050714
  • GO:0051591
  • GO:0055085
  • GO:0071333
  • GO:0098772
  • GO:1901701
  • GO:1904619
  • GO:1904659
  • ILMN_2743236
  • Msa.2390.0_at
  • mMC008335
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • INS1_MOUSE
  • Q545I7
  • Q9D907
sequenceLength 108
species [Species:48892] Mus musculus
stId uniprot:P01325
url http://purl.uniprot.org/uniprot/P01325

Referrals

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(referenceSequence)
(secondReferenceSequence)
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