Reactome | UniProt:O95813 CER1

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UniProt:O95813 CER1 Show undefined attributes

chain	signal peptide:1-17 chain:18-267
checksum	C9FB048CD8558ED7
comment	FUNCTION Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak (By similarity).SUBUNIT Forms monomers and predominantly dimers.SUBCELLULAR LOCATION N-glycosylated.SIMILARITY Belongs to the DAN family.SEQUENCE CAUTION Truncated C-terminus.
created	[InstanceEdit:201812] Jassal, B, 2007-09-25 08:39:03
crossReference	[DatabaseIdentifier:12444374] RefSeq:NP_005445.1 [DatabaseIdentifier:12281992] Pharos - Targets:O95813 [DatabaseIdentifier:12259926] PRO:O95813 [DatabaseIdentifier:12121667] OpenTargets:ENSG00000147869 [DatabaseIdentifier:11837179] HPA:ENSG00000147869-CER1 [DatabaseIdentifier:11799603] GlyGen:O95813 [DatabaseIdentifier:11784076] GeneCards:CER1 [DatabaseIdentifier:11743814] ENSEMBL:ENST00000380911 [DatabaseIdentifier:11621115] ENSEMBL:ENSP00000370297 [DatabaseIdentifier:11507413] ENSEMBL:ENSG00000147869
databaseName	UniProt
dbId	201815
description	recommendedName: Cerberus alternativeName: Cerberus-related protein alternativeName: DAN domain family member 4
displayName	UniProt:O95813 CER1
geneName	CER1 DAND4
identifier	O95813
isSequenceChanged	false
keyword	Cytokine Direct protein sequencing Disulfide bond Glycoprotein Proteomics identification Reference proteome Secreted Signal
modified	[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType	Protein
name	CER1
otherIdentifier	11732296_at 17092526 221378_PM_at 221378_at 3199499 3199501 3199502 3199503 3199504 3199505 3199506 8160163 9350 A_23_P329798 GE523227 GO:0001657 GO:0003002 GO:0003419 GO:0005125 GO:0005576 GO:0005615 GO:0007369 GO:0007399 GO:0008283 GO:0008285 GO:0009888 GO:0009948 GO:0009952 GO:0016015 GO:0023019 GO:0030282 GO:0030514 GO:0032926 GO:0035582 GO:0036122 GO:0042074 GO:0042803 GO:0048018 GO:0048263 GO:0048513 GO:0048731 GO:0048856 GO:0048870 GO:0061371 GO:0071276 GO:0098772 GO:2000381 HMNXSV003023090 ILMN_1690192 ILMN_2115143 PH_hs_0013186 PH_hs_0015406 PH_hs_0032315 TC09000919.hg g4885134_3p_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-9921118] CER1 [exocytic vesicle] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-201831] CER1 [extracellular region] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:12760777] UCSC:O95813 CER1 [ReferenceDNASequence:12107340] OMIM:603777 CER1 [ReferenceDNASequence:12086468] NCBI Gene:9350 CER1 [ReferenceDNASequence:12002375] Monarch:9350 CER1 [ReferenceDNASequence:11910526] KEGG:hsa:9350 CER1 [ReferenceDNASequence:11815700] HGNC:1862 CER1 [ReferenceDNASequence:11440280] dbSNP Gene:9350 CER1 [ReferenceDNASequence:11407909] CTD Gene:9350 CER1 [ReferenceDNASequence:11402758] COSMIC - genes:CER1 CER1 [ReferenceDNASequence:11372586] BioGPS Gene:9350 CER1 [ReferenceDNASequence:ensembl:ENSG00000147869] ENSEMBL:ENSG00000147869 CER1
referenceTranscript	[ReferenceRNASequence:12625926] RefSeq:NM_005454.3 CER1
schemaClass	ReferenceGeneProduct
secondaryIdentifier	CER1_HUMAN Q6ISJ1 Q6ISJ6 Q6ISQ2 Q6ISS1
sequenceLength	267
species	[Species:48887] Homo sapiens
stId	uniprot:O95813
url	http://purl.uniprot.org/uniprot/O95813

Referrals

(interactor)	[UndirectedInteraction:11223799] UniProt:P35813 <-> UniProt:O95813 (IntAct)
(referenceEntity)	[EntityWithAccessionedSequence:R-HSA-9921118] CER1 [exocytic vesicle] [EntityWithAccessionedSequence:R-HSA-201831] CER1 [extracellular region]