Reactome | UniProt:O95294 RASAL1

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UniProt:O95294 RASAL1 Show undefined attributes

chain	chain:1-804
checksum	5D0065A093487FD0
comment	FUNCTION Probable inhibitory regulator of the Ras-cyclic AMP pathway (PubMed:9751798). Plays a role in dendrite formation by melanocytes (PubMed:23999003).COFACTOR Highly expressed in thyroid and adrenal medulla, lower expression in brain, spinal cord and trachea (PubMed:9751798). Expressed in melanocytes (PubMed:23999003).SEQUENCE CAUTION Extended N-terminus.
crossReference	[DatabaseIdentifier:11459399] ENSEMBL:ENSG00000111344 [DatabaseIdentifier:11551726] ENSEMBL:ENSP00000395920 [DatabaseIdentifier:11551728] ENSEMBL:ENSP00000450244 [DatabaseIdentifier:11551725] ENSEMBL:ENSP00000448510 [DatabaseIdentifier:11551727] ENSEMBL:ENSP00000261729 [DatabaseIdentifier:11674425] ENSEMBL:ENST00000261729 [DatabaseIdentifier:11674427] ENSEMBL:ENST00000548055 [DatabaseIdentifier:11674424] ENSEMBL:ENST00000546530 [DatabaseIdentifier:11674426] ENSEMBL:ENST00000446861 [DatabaseIdentifier:11793042] GeneCards:RASAL1 [DatabaseIdentifier:11846030] HPA:ENSG00000111344-RASAL1 [DatabaseIdentifier:12130684] OpenTargets:ENSG00000111344 [DatabaseIdentifier:12252904] PRO:O95294 [DatabaseIdentifier:12290884] Pharos - Targets:O95294 [DatabaseIdentifier:12338911] RefSeq:XP_006719704.1 [DatabaseIdentifier:12338912] RefSeq:NP_001381014.1 [DatabaseIdentifier:12338914] RefSeq:XP_005254007.1 [DatabaseIdentifier:12338915] RefSeq:NP_001381012.1 [DatabaseIdentifier:12338905] RefSeq:XP_047285632.1 [DatabaseIdentifier:12338909] RefSeq:NP_001381010.1 [DatabaseIdentifier:12338913] RefSeq:NP_001381013.1 [DatabaseIdentifier:12338908] RefSeq:NP_001381011.1 [DatabaseIdentifier:12338907] RefSeq:NP_001288131.1 [DatabaseIdentifier:12338910] RefSeq:NP_001180450.1 [DatabaseIdentifier:12338916] RefSeq:NP_004649.2 [DatabaseIdentifier:12338906] RefSeq:NP_001180449.1
databaseName	UniProt
dbId	63766
description	recommendedName: fullName evidence="12"RasGAP-activating-like protein 1 alternativeName: fullName evidence="13"RAS protein activator like 1 alternativeName: fullName evidence="10"Ras GTPase-activating-like protein
displayName	UniProt:O95294 RASAL1
geneName	RASAL1 RASAL
identifier	O95294
isSequenceChanged	false
keyword	Alternative splicing Calcium Differentiation GTPase activation Metal-binding Proteomics identification Reference proteome Repeat Zinc Zinc-finger
modified	[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType	Protein
name	RASAL1
otherIdentifier	11731058_a_at 11750696_a_at 16770475 219752_PM_at 219752_at 233144_3p_s_at 233144_PM_s_at 233144_s_at 3472180 3472182 3472184 3472185 3472186 3472187 3472188 3472189 3472191 3472192 3472193 3472194 3472195 3472196 3472197 3472200 3472201 3472202 3472203 3472204 3472205 3472206 3472207 3472208 3472209 3472210 3472211 3472212 3472215 3472217 3472218 3472219 3472220 7966542 81768_at 8437 86396_at A_23_P139600 GE61873 GO:0005096 GO:0005543 GO:0005829 GO:0005886 GO:0007165 GO:0008270 GO:0030154 GO:0035556 GO:0043087 GO:0046580 GO:0046872 GO:0071277 GO:0098772 GO:1902531 GO:1903861 HMNXSV003038145 Hs.198312.1.S1_3p_a_at ILMN_1793517 PH_hs_0011684 TC12001982.hg g4759025_3p_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-5658233] RASAL1 [cytosol] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:ensembl:ENSG00000111344] ENSEMBL:ENSG00000111344 RASAL1 [ReferenceDNASequence:12730597] UCSC:O95294 RASAL1 [ReferenceDNASequence:11324099] BioGPS Gene:8437 RASAL1 [ReferenceDNASequence:11398418] COSMIC - genes:RASAL1 RASAL1 [ReferenceDNASequence:11421395] CTD Gene:8437 RASAL1 [ReferenceDNASequence:11435230] dbSNP Gene:8437 RASAL1 [ReferenceDNASequence:11824729] HGNC:9873 RASAL1 [ReferenceDNASequence:11866613] KEGG:hsa:8437 RASAL1 [ReferenceDNASequence:11953888] Monarch:8437 RASAL1 [ReferenceDNASequence:12037981] NCBI Gene:8437 RASAL1 [ReferenceDNASequence:12115217] OMIM:604118 RASAL1
referenceTranscript	[ReferenceRNASequence:12520800] RefSeq:NM_004658.3 RASAL1 [ReferenceRNASequence:12520801] RefSeq:XM_006719641.4 RASAL1 [ReferenceRNASequence:12520796] RefSeq:NM_001394085.1 RASAL1 [ReferenceRNASequence:12520795] RefSeq:NM_001301202.2 RASAL1 [ReferenceRNASequence:12520793] RefSeq:NM_001193521.3 RASAL1 [ReferenceRNASequence:12520799] RefSeq:NM_001394083.1 RASAL1 [ReferenceRNASequence:12520797] RefSeq:NM_001394082.1 RASAL1 [ReferenceRNASequence:12520794] RefSeq:NM_001394084.1 RASAL1 [ReferenceRNASequence:12520804] RefSeq:NM_001394081.1 RASAL1 [ReferenceRNASequence:12520802] RefSeq:XM_047429676.1 RASAL1 [ReferenceRNASequence:12520803] RefSeq:XM_005253950.5 RASAL1 [ReferenceRNASequence:12520798] RefSeq:NM_001193520.2 RASAL1
schemaClass	ReferenceGeneProduct
secondaryIdentifier	RASL1_HUMAN B7ZKM4 C9JFK5 F8VQX1 Q52M03 Q59H24 Q96CC7
sequenceLength	804
species	[Species:48887] Homo sapiens
stId	uniprot:O95294
url	http://purl.uniprot.org/uniprot/O95294

Referrals

(referenceEntity)

[EntityWithAccessionedSequence:R-HSA-5658233] RASAL1 [cytosol]

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