UniProt:O94864 SUPT7L

chain
  • chain:1-414
checksum 59724A96353D44D5
comment
  • SUBUNIT Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, SUPT7L, GCN5L2, TAF5L, TAF6L, TADA3L, TAD1L, TAF10, TAF12 and TAF9.SUBCELLULAR LOCATION Expressed at high levels in adenocarcinomas and gliomas and low in esophageal cancers and malignant hematological disease. Also expressed at high level in the thymus, low in peripheral blood mononuclear cells, and lowest in the stomach, small intestine, and skeletal muscle.PTM Sumoylated.DISEASE The disease may be caused by variants affecting the gene represented in this entry.
crossReference
databaseName UniProt
dbId 65144
description
  • recommendedName: STAGA complex 65 subunit gamma alternativeName: Adenocarcinoma antigen ART1 alternativeName: SPTF-associated factor 65 gamma shortName: STAF65gamma alternativeName: Suppressor of Ty 7-like
displayName UniProt:O94864 SUPT7L
geneName
  • SUPT7L
  • KIAA0764
identifier O94864
isSequenceChanged false
keyword
  • 3D-structure
  • Alternative splicing
  • Congenital generalized lipodystrophy
  • Isopeptide bond
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Transcription
  • Transcription regulation
  • Ubl conjugation
modified [InstanceEdit:9983091] Weiser, Joel, 2026-02-20
moleculeType Protein
name
  • SUPT7L
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • ST65G_HUMAN
  • B4E3W3
  • Q6IB21
  • Q9H2T6
sequenceLength 414
species [Species:48887] Homo sapiens
stId uniprot:O94864
url http://purl.uniprot.org/uniprot/O94864
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