UniProt:O77622 CCT6

chain
  • initiator methionine:1
  • chain:2-531
checksum 2A5007DA986A5338
comment
  • FUNCTION Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance.CATALYTIC ACTIVITY ATP + H2O = ADP + phosphate + H(+)SUBUNIT Component of the chaperonin-containing T-complex (TRiC), a hexadecamer composed of two identical back-to-back stacked rings enclosing a protein folding chamber. Each ring is made up of eight different subunits: TCP1/CCT1, CCT2, CCT3, CCT4, CCT5, CCT6A/CCT6, CCT7, CCT8. Interacts with PACRG.INTERACTION Belongs to the TCP-1 chaperonin family.
created [InstanceEdit:391401] Matthews, L, 2009-02-21 05:12:16
crossReference
databaseName UniProt
dbId 391441
description
  • recommendedName: T-complex protein 1 subunit zeta shortName: TCP-1-zeta ecNumber evidence="1"3.6.1.- alternativeName: CCT-zeta
displayName UniProt:O77622 CCT6
geneName
  • CCT6
identifier O77622
isSequenceChanged false
keyword
  • Acetylation
  • ATP-binding
  • Chaperone
  • Cytoplasm
  • Hydrolase
  • Isopeptide bond
  • Magnesium
  • Metal-binding
  • Nucleotide-binding
  • Phosphoprotein
  • Reference proteome
  • Ubl conjugation
modified [InstanceEdit:9963647] Weiser, Joel, 2025-08-15
moleculeType Protein
name
  • CCT6
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • TCPZ_RABIT
sequenceLength 531
species [Species:49130] Oryctolagus cuniculus
stId uniprot:O77622
url http://purl.uniprot.org/uniprot/O77622
Cite Us!