UniProt:O75528 TADA3

chain
  • chain:1-432
checksum C86153CFA83F9226
comment
  • FUNCTION Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53-dependent transcriptional activation. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.SUBUNIT The PCAF complex is composed of a number of TBP-associated factors (TAFS), such as TAF5, TAF5L, TAF6, TAF6L, TAF9, TAF10 and TAF12, PCAF, and also PCAF-associated factors (PAFs), such as TADA2L/ADA2, TADA3L/ADA3 and SPT3. Interacts directly with TADA2L and PCAF and also with the high-risk HPV oncoprotein E6. Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9. Component of the TFTC-HAT complex. Component of the ADA2A-containing complex (ATAC), composed of KAT14, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1.INTERACTION Ubiquitously expressed.SIMILARITY Belongs to the NGG1 family.
created [InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10
crossReference
databaseName UniProt
dbId 154651
description
  • recommendedName: Transcriptional adapter 3 alternativeName: ADA3 homolog shortName: hADA3 alternativeName: STAF54 alternativeName: Transcriptional adapter 3-like shortName: ADA3-like protein
displayName UniProt:O75528 TADA3
geneName
  • TADA3
  • ADA3
  • TADA3L
identifier O75528
isSequenceChanged false
keyword
  • Acetylation
  • Alternative splicing
  • Coiled coil
  • Isopeptide bond
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Transcription
  • Transcription regulation
  • Ubl conjugation
modified [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType Protein
name
  • TADA3
otherIdentifier
  • 10474
  • 11719001_a_at
  • 11736036_a_at
  • 11736037_x_at
  • 11736038_x_at
  • 11748818_x_at
  • 16950569
  • 211221_PM_at
  • 211221_at
  • 215273_PM_s_at
  • 215273_s_at
  • 2662357
  • 2662358
  • 2662361
  • 2662362
  • 2662363
  • 2662364
  • 2662365
  • 2662366
  • 2662367
  • 2662368
  • 2662370
  • 2662371
  • 2662372
  • 2662373
  • 2662374
  • 2662376
  • 2662377
  • 2662378
  • 2662379
  • 2662381
  • 35749_at
  • 3651116
  • 8085220
  • A_23_P109821
  • A_23_P305016
  • GE56484
  • GO:0000122
  • GO:0000124
  • GO:0000278
  • GO:0003713
  • GO:0005515
  • GO:0005634
  • GO:0005654
  • GO:0006282
  • GO:0006325
  • GO:0006355
  • GO:0006357
  • GO:0010628
  • GO:0016922
  • GO:0019904
  • GO:0030520
  • GO:0031647
  • GO:0033276
  • GO:0043226
  • GO:0043484
  • GO:0045893
  • GO:0045995
  • GO:0051302
  • GO:0051726
  • GO:0072686
  • GO:0140672
  • HMNXSV003025515
  • HMNXSV003033240
  • Hs.158196.3.S1_3p_a_at
  • ILMN_1674866
  • ILMN_1770141
  • ILMN_1792176
  • PH_hs_0024391
  • TC03001150.hg
  • g5911971_3p_at
  • g5911971_3p_x_at
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • TADA3_HUMAN
  • Q6FI83
  • Q9UFS2
sequenceLength 432
species [Species:48887] Homo sapiens
stId uniprot:O75528
url http://purl.uniprot.org/uniprot/O75528

Referrals

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