Reactome | UniProt:O75346 ZNF253

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UniProt:O75346 ZNF253 Show undefined attributes

chain	chain:1-499
checksum	783F3352A58AC767
comment	FUNCTION May function as a transcription factor. Seem to have a transcriptional repression activity.INTERACTION Expressed in bone marrow and in monocytic and immature erythroid cell lines.SIMILARITY Belongs to the krueppel C2H2-type zinc-finger protein family.
crossReference	[DatabaseIdentifier:12329816] RefSeq:NP_066385.2 [DatabaseIdentifier:12329814] RefSeq:NP_001318062.1 [DatabaseIdentifier:12329815] RefSeq:NP_001318063.1 [DatabaseIdentifier:12288012] Pharos - Targets:O75346 [DatabaseIdentifier:12248823] PRO:O75346 [DatabaseIdentifier:12127783] OpenTargets:ENSG00000256771 [DatabaseIdentifier:11843183] HPA:ENSG00000256771-ZNF253 [DatabaseIdentifier:11805983] GlyGen:O75346 [DatabaseIdentifier:11790163] GeneCards:ZNF253 [DatabaseIdentifier:11668221] ENSEMBL:ENST00000355650 [DatabaseIdentifier:11668220] ENSEMBL:ENST00000589717 [DatabaseIdentifier:11545521] ENSEMBL:ENSP00000347868 [DatabaseIdentifier:11545522] ENSEMBL:ENSP00000468720 [DatabaseIdentifier:11455053] ENSEMBL:ENSG00000256771
databaseName	UniProt
dbId	67966
description	recommendedName: Zinc finger protein 253 alternativeName: Bone marrow zinc finger 1 shortName: BMZF-1 alternativeName: Zinc finger protein 411
displayName	UniProt:O75346 ZNF253
geneName	ZNF253 BMZF1 ZNF411
identifier	O75346
isSequenceChanged	false
keyword	Alternative splicing DNA-binding Metal-binding Nucleus Proteomics identification Reference proteome Repeat Repressor Transcription Transcription regulation Zinc Zinc-finger
modified	[InstanceEdit:9983091] Weiser, Joel, 2026-02-20
moleculeType	Protein
name	ZNF253
otherIdentifier	11739672_x_at 16860097 206900_3p_x_at 206900_PM_x_at 206900_x_at 242919_PM_at 242919_at 35572_f_at 35573_r_at 3826053 3826055 3826056 3826057 3826058 3826059 3826060 3826061 3826062 3826063 3826064 3826065 3826066 3826067 3826068 3826069 3826070 3826071 3826072 3826073 3826074 3826085 3826086 3826097 3826183 3826248 3856203 3856220 3856246 56242 69848_r_at 8027241 8035779 8180217 A_14_P111540 A_23_P165214 A_24_P22981 GE54330 GO:0000978 GO:0000981 GO:0003677 GO:0005634 GO:0006355 GO:0006357 GO:0008270 GO:0045892 GO:0046872 HMNXSV003013575 Hs.201677.0.A1_3p_at ILMN_1769099 PH_hs_0035911 TC19000381.hg g10567821_3p_at g10567821_3p_x_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-1027400] ZNF253 [nucleoplasm] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:12727977] UCSC:O75346 ZNF253 [ReferenceDNASequence:12112616] OMIM:606954 ZNF253 [ReferenceDNASequence:12033861] NCBI Gene:56242 ZNF253 [ReferenceDNASequence:11949768] Monarch:56242 ZNF253 [ReferenceDNASequence:11862853] KEGG:hsa:56242 ZNF253 [ReferenceDNASequence:11821821] HGNC:13497 ZNF253 [ReferenceDNASequence:11434860] dbSNP Gene:56242 ZNF253 [ReferenceDNASequence:11417354] CTD Gene:56242 ZNF253 [ReferenceDNASequence:11398083] COSMIC - genes:ZNF253 ZNF253 [ReferenceDNASequence:11319979] BioGPS Gene:56242 ZNF253 [ReferenceDNASequence:ensembl:ENSG00000256771] ENSEMBL:ENSG00000256771 ZNF253
referenceTranscript	[ReferenceRNASequence:12511724] RefSeq:NM_001331134.1 ZNF253 [ReferenceRNASequence:12511723] RefSeq:NM_001331133.1 ZNF253 [ReferenceRNASequence:12511722] RefSeq:NM_021047.3 ZNF253
schemaClass	ReferenceGeneProduct
secondaryIdentifier	ZN253_HUMAN A4FVA7 Q0P6G3 Q6P0L2 Q8NCA3 Q8NCF9
sequenceLength	499
species	[Species:48887] Homo sapiens
stId	uniprot:O75346
url	http://purl.uniprot.org/uniprot/O75346

Referrals

(referenceEntity)

[EntityWithAccessionedSequence:R-HSA-1027400] ZNF253 [nucleoplasm]