UniProt:O43897 TLL1

chain
  • signal peptide:1-30
  • propeptide:31-147
  • chain:148-1013
checksum 0FDDB6E8E9032DCC
comment
  • FUNCTION Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis.COFACTOR Binds 1 zinc ion per subunit.SUBCELLULAR LOCATION The disease is caused by variants affecting the gene represented in this entry.
created [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
crossReference
databaseName UniProt
dbId 251387
description
  • recommendedName: Tolloid-like protein 1 ecNumber: 3.4.24.-
displayName UniProt:O43897 TLL1
geneName
  • TLL1
  • TLL
identifier O43897
isSequenceChanged false
keyword
  • 3D-structure
  • Alternative splicing
  • Atrial septal defect
  • Calcium
  • Developmental protein
  • Differentiation
  • Disease variant
  • Disulfide bond
  • EGF-like domain
  • Glycoprotein
  • Hydrolase
  • Metal-binding
  • Metalloprotease
  • Protease
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
  • Zinc
  • Zymogen
modified [InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType Protein
name
  • TLL1
otherIdentifier
  • 11737086_a_at
  • 11737087_at
  • 11737088_at
  • 11737089_a_at
  • 11762620_at
  • 1555071_PM_at
  • 1555071_at
  • 16972198
  • 206415_PM_at
  • 206415_at
  • 2750755
  • 2750756
  • 2750757
  • 2750758
  • 2750759
  • 2750760
  • 2750761
  • 2750766
  • 2750767
  • 2750774
  • 2750787
  • 2750788
  • 2750789
  • 2750790
  • 2750791
  • 2750792
  • 2750793
  • 2750795
  • 2750799
  • 2750801
  • 2750804
  • 2750805
  • 2750806
  • 2750807
  • 2750808
  • 2750811
  • 2750812
  • 2750814
  • 2750815
  • 2750816
  • 2750817
  • 2750818
  • 2750819
  • 2750824
  • 2750829
  • 2750832
  • 2750833
  • 2750834
  • 2750835
  • 2750836
  • 31333_at
  • 7092
  • 8098214
  • 86964_at
  • A_14_P101657
  • A_14_P109377
  • A_14_P122103
  • A_14_P127810
  • A_21_P0000156
  • A_23_P427645
  • A_24_P145163
  • GE473790
  • GE475997
  • GO:0001501
  • GO:0004222
  • GO:0004252
  • GO:0005509
  • GO:0005576
  • GO:0005615
  • GO:0006508
  • GO:0008233
  • GO:0008237
  • GO:0008270
  • GO:0009953
  • GO:0016020
  • GO:0016485
  • GO:0016787
  • GO:0030154
  • GO:0030198
  • GO:0030199
  • GO:0046872
  • GO:0048856
  • HMNXSV003008314
  • HMNXSV003048717
  • Hs.129700.0.S3_3p_at
  • Hs2.129700.2.S1_3p_at
  • ILMN_1699814
  • PH_hs_0007588
  • TC04000833.hg
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • TLL1_HUMAN
  • B2RMU2
  • Q96AN3
  • Q9NQS4
sequenceLength 1013
species [Species:48887] Homo sapiens
stId uniprot:O43897
url http://purl.uniprot.org/uniprot/O43897
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