UniProt:O43678 NDUFA2

chain
  • initiator methionine:1
  • chain:2-99
checksum EF026F193CAF1DF7
comment
  • FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.SUBUNIT Complex I is composed of 45 different subunits.SUBCELLULAR LOCATION The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the complex I NDUFA2 subunit family.
crossReference
databaseName UniProt
dbId 60179
description
  • recommendedName: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 alternativeName: Complex I-B8 shortName: CI-B8 alternativeName: NADH-ubiquinone oxidoreductase B8 subunit
displayName UniProt:O43678 NDUFA2
geneName
  • NDUFA2
identifier O43678
isSequenceChanged false
keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Disulfide bond
  • Electron transport
  • Membrane
  • Mitochondrion
  • Mitochondrion inner membrane
  • Primary mitochondrial disease
  • Proteomics identification
  • Reference proteome
  • Respiratory chain
  • Transport
modified [InstanceEdit:9963647] Weiser, Joel, 2025-08-15
moleculeType Protein
name
  • NDUFA2
otherIdentifier
  • 11718831_at
  • 17000800
  • 209223_PM_at
  • 209223_at
  • 209224_PM_s_at
  • 209224_s_at
  • 2878447
  • 2878449
  • 2878450
  • 2878451
  • 2878455
  • 2878456
  • 2878457
  • 2878458
  • 40546_s_at
  • 4695
  • 63514_at
  • 7894479
  • 7895842
  • 8114618
  • A_23_P257795
  • A_24_P12218
  • GE54402
  • GO:0001835
  • GO:0005739
  • GO:0005743
  • GO:0006091
  • GO:0006120
  • GO:0008137
  • GO:0009060
  • GO:0016020
  • GO:0016491
  • GO:0031966
  • GO:0042776
  • GO:0045271
  • GO:0055085
  • GO:0055086
  • GO:1901135
  • GO:1902600
  • HMNXSV003053434
  • Hs.163867.0.S1_3p_at
  • PH_hs_0009907
  • PH_hs_0035627
  • TC05001862.hg
  • TC05003269.hg
  • g13277539_3p_a_at
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • NDUA2_HUMAN
  • D6RJD6
  • Q6IAY8
sequenceLength 99
species [Species:48887] Homo sapiens
stId uniprot:O43678
url http://purl.uniprot.org/uniprot/O43678
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