FUNCTION Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.SUBUNIT Complex I is composed of 45 different subunits.SUBCELLULAR LOCATION Methylation at His residues by METTL9 enhances complex I-mediated mitochondrial respiration.DISEASE The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the complex I NDUFB3 subunit family.
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