UniProt:O43390 HNRNPR

chain
  • initiator methionine:1
  • chain:2-633
checksum 088341F6465ED46F
comment
  • FUNCTION Component of ribonucleosomes, which are complexes of at least 20 other different heterogeneous nuclear ribonucleoproteins (hnRNP). hnRNP play an important role in processing of precursor mRNA in the nucleus.SUBUNIT Identified in the spliceosome C complex. Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Interacts with GTPBP1.INTERACTION Localized in cytoplasmic mRNP granules containing untranslated mRNAs. The tyrosine phosphorylated form bound to RNA is found in microsomes (By similarity).ALTERNATIVE PRODUCTS The disease is caused by variants affecting the gene represented in this entry.MISCELLANEOUS Expression is low and neural-specific.
crossReference
databaseName UniProt
dbId 71950
description
  • recommendedName: Heterogeneous nuclear ribonucleoprotein R shortName: hnRNP R
displayName UniProt:O43390 HNRNPR
geneName
  • HNRNPR
  • HNRPR
identifier O43390
isSequenceChanged false
keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Cytoplasm
  • Direct protein sequencing
  • Disease variant
  • Endoplasmic reticulum
  • Intellectual disability
  • Isopeptide bond
  • Microsome
  • mRNA processing
  • mRNA splicing
  • Nucleus
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Ribonucleoprotein
  • RNA-binding
  • Spliceosome
  • Ubl conjugation
modified [InstanceEdit:9963647] Weiser, Joel, 2025-08-15
moleculeType Protein
name
  • HNRNPR
otherIdentifier
  • 10236
  • 11725617_s_at
  • 11747482_a_at
  • 11758936_at
  • 16683271
  • 208765_PM_s_at
  • 208765_s_at
  • 208766_PM_s_at
  • 208766_s_at
  • 232004_PM_at
  • 232004_at
  • 2401281
  • 2401282
  • 2401283
  • 2401284
  • 2401285
  • 2401286
  • 2401287
  • 2401288
  • 2401289
  • 2401290
  • 2401291
  • 2401292
  • 2401293
  • 2401294
  • 2401295
  • 2401297
  • 2401298
  • 2401301
  • 2401306
  • 2401309
  • 2401313
  • 2401316
  • 2401317
  • 2401318
  • 2401319
  • 2401320
  • 2401321
  • 2401322
  • 2401323
  • 2401324
  • 243558_PM_at
  • 243558_at
  • 3280848
  • 39792_at
  • 44995_at
  • 48254_at
  • 72503_at
  • 7913571
  • 80274_at
  • A_19_P00318431
  • A_19_P00803399
  • A_23_P45726
  • A_24_P724984
  • GE505345
  • GE54017
  • GE55931
  • GO:0000398
  • GO:0003676
  • GO:0003723
  • GO:0003729
  • GO:0005515
  • GO:0005634
  • GO:0005654
  • GO:0005681
  • GO:0005737
  • GO:0005783
  • GO:0006397
  • GO:0008380
  • GO:0016071
  • GO:0071013
  • GO:1990904
  • HMNXSV003030058
  • Hs.15265.0.S1_3p_a_at
  • Hs.44392.0.S1_3p_at
  • Hs.8412.0.S1_3p_at
  • ILMN_2175894
  • PH_hs_0022012
  • PH_hs_0041191
  • TC01002339.hg
  • TC01002340.hg
  • g12655184_3p_a_at
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • HNRPR_HUMAN
  • Q2L7G6
  • Q5TEH1
  • Q9BV64
  • S4R3J4
sequenceLength 633
species [Species:48887] Homo sapiens
stId uniprot:O43390
url http://purl.uniprot.org/uniprot/O43390
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