Reactome | UniProt:A6NI73 LILRA5

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UniProt:A6NI73 LILRA5 Show undefined attributes

chain	signal peptide:1-41 chain:42-299
checksum	F5EE25361D4E0F02
comment	FUNCTION May play a role in triggering innate immune responses. Does not seem to play a role for any class I MHC antigen recognition.SUBCELLULAR LOCATION Expressed mostly in tissues of the hematopoietic system, including bone marrow, spleen, lymph node and peripheral leukocytes. Among leukocytes, monocytes and neutrophils express the highest level. Expressed in CD14+ monocytes, but not in T-cells, B-cells or natural killer (NK) cells (at protein level).
created	[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
crossReference	[DatabaseIdentifier:11847911] HPA:ENSG00000187116-LILRA5 [DatabaseIdentifier:12390330] RefSeq:NP_871714.1 [DatabaseIdentifier:12390329] RefSeq:NP_067073.1 [DatabaseIdentifier:12390331] RefSeq:NP_870994.1 [DatabaseIdentifier:12390328] RefSeq:NP_871715.1 [DatabaseIdentifier:12292766] Pharos - Targets:A6NI73 [DatabaseIdentifier:12275833] PRO:A6NI73 [DatabaseIdentifier:12226093] PDB:2D3V [DatabaseIdentifier:12132595] OpenTargets:ENSG00000187116 [DatabaseIdentifier:11482534] ENSEMBL:ENSG00000274113 [DatabaseIdentifier:11482537] ENSEMBL:ENSG00000278355 [DatabaseIdentifier:11482538] ENSEMBL:ENSG00000187116 [DatabaseIdentifier:11482535] ENSEMBL:ENSG00000275404 [DatabaseIdentifier:11482536] ENSEMBL:ENSG00000274914 [DatabaseIdentifier:11584188] ENSEMBL:ENSP00000478354 [DatabaseIdentifier:11584180] ENSEMBL:ENSP00000480458 [DatabaseIdentifier:11584181] ENSEMBL:ENSP00000483958 [DatabaseIdentifier:11584190] ENSEMBL:ENSP00000480382 [DatabaseIdentifier:11584192] ENSEMBL:ENSP00000477785 [DatabaseIdentifier:11584177] ENSEMBL:ENSP00000482658 [DatabaseIdentifier:11584187] ENSEMBL:ENSP00000482882 [DatabaseIdentifier:11584178] ENSEMBL:ENSP00000480204 [DatabaseIdentifier:11584189] ENSEMBL:ENSP00000484372 [DatabaseIdentifier:11584183] ENSEMBL:ENSP00000484869 [DatabaseIdentifier:11584182] ENSEMBL:ENSP00000404236 [DatabaseIdentifier:11584185] ENSEMBL:ENSP00000484775 [DatabaseIdentifier:11584191] ENSEMBL:ENSP00000484062 [DatabaseIdentifier:11584186] ENSEMBL:ENSP00000483992 [DatabaseIdentifier:11584179] ENSEMBL:ENSP00000480436 [DatabaseIdentifier:11584184] ENSEMBL:ENSP00000484785 [DatabaseIdentifier:11706887] ENSEMBL:ENST00000620898 [DatabaseIdentifier:11706878] ENSEMBL:ENST00000621042 [DatabaseIdentifier:11706891] ENSEMBL:ENST00000620692 [DatabaseIdentifier:11706881] ENSEMBL:ENST00000613559 [DatabaseIdentifier:11706886] ENSEMBL:ENST00000616133 [DatabaseIdentifier:11706888] ENSEMBL:ENST00000614299 [DatabaseIdentifier:11706883] ENSEMBL:ENST00000615820 [DatabaseIdentifier:11706882] ENSEMBL:ENST00000618711 [DatabaseIdentifier:11706880] ENSEMBL:ENST00000619516 [DatabaseIdentifier:11706885] ENSEMBL:ENST00000486742 [DatabaseIdentifier:11706876] ENSEMBL:ENST00000620091 [DatabaseIdentifier:11706877] ENSEMBL:ENST00000621482 [DatabaseIdentifier:11706884] ENSEMBL:ENST00000612621 [DatabaseIdentifier:11706890] ENSEMBL:ENST00000432233 [DatabaseIdentifier:11706879] ENSEMBL:ENST00000612266 [DatabaseIdentifier:11706889] ENSEMBL:ENST00000611164 [DatabaseIdentifier:11794943] GeneCards:LILRA5 [DatabaseIdentifier:11810826] GlyGen:A6NI73
databaseName	UniProt
dbId	235197
description	recommendedName: Leukocyte immunoglobulin-like receptor subfamily A member 5 alternativeName: CD85 antigen-like family member F alternativeName: Immunoglobulin-like transcript 11 shortName: ILT-11 alternativeName: Leukocyte immunoglobulin-like receptor 9 shortName: LIR-9 cdAntigenNameCD85f/cdAntigenName
displayName	UniProt:A6NI73 LILRA5
geneName	LILRA5 ILT11 LILRB7 LIR9
identifier	A6NI73
isSequenceChanged	false
keyword	3D-structure Alternative splicing Cell membrane Disulfide bond Glycoprotein Immunity Immunoglobulin domain Innate immunity Membrane Proteomics identification Receptor Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix
modified	[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
moleculeType	Protein
name	LILRA5
otherIdentifier	11738698_x_at 11738903_a_at 11742375_a_at 1555634_PM_a_at 1555634_a_at 1555643_PM_s_at 1555643_s_at 16875448 16875459 16875461 16875463 215838_PM_at 215838_at 353514 3841402 3841405 3841554 3841581 3870672 3870751 3870759 3870760 3870761 3870762 3870763 3870764 3870765 3870766 3870767 3870768 3870769 3870770 3870771 3870772 3870773 3870774 3870775 3870776 3870777 3870778 3870779 3870780 3870781 3870785 8039236 A_23_P107847 A_24_P370172 GE85061 GO:0002376 GO:0002764 GO:0005576 GO:0005615 GO:0005886 GO:0009986 GO:0016020 GO:0019221 GO:0032396 GO:0032695 GO:0032696 GO:0032731 GO:0032733 GO:0032755 GO:0032760 GO:0043410 GO:0045087 GO:0050729 GO:0050867 GO:0051928 GO:0061098 GO:0098542 HMNXSV003040761 HMNXSV003055869 Hs.284190.0.S1_3p_at Hs2.113277.5.S1_3p_a_at Hs2.113277.6.S1_3p_x_at ILMN_1726545 ILMN_1787662 ILMN_2266595 ILMN_2357419 PH_hs_0026737 TC19002719.hg p8450
physicalEntity	[EntityWithAccessionedSequence:R-HSA-6786741] LILRA5 [plasma membrane] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:ensembl:ENSG00000187116] ENSEMBL:ENSG00000187116 LILRA5 [ReferenceDNASequence:12694284] UCSC:A6NI73 LILRA5 [ReferenceDNASequence:12116935] OMIM:606047 LILRA5 [ReferenceDNASequence:12061871] NCBI Gene:353514 LILRA5 [ReferenceDNASequence:11977778] Monarch:353514 LILRA5 [ReferenceDNASequence:11887973] KEGG:hsa:353514 LILRA5 [ReferenceDNASequence:11347989] BioGPS Gene:353514 LILRA5 [ReferenceDNASequence:11393295] COSMIC - genes:LILRA5 LILRA5 [ReferenceDNASequence:11423797] CTD Gene:353514 LILRA5 [ReferenceDNASequence:11429235] dbSNP Gene:353514 LILRA5 [ReferenceDNASequence:11826640] HGNC:16309 LILRA5
referenceTranscript	[ReferenceRNASequence:12572091] RefSeq:NM_181985.4 LILRA5 [ReferenceRNASequence:12572089] RefSeq:NM_021250.4 LILRA5 [ReferenceRNASequence:12572092] RefSeq:NM_181986.3 LILRA5 [ReferenceRNASequence:12572090] RefSeq:NM_181879.3 LILRA5
schemaClass	ReferenceGeneProduct
secondaryIdentifier	LIRA5_HUMAN A6NHI3
sequenceLength	299
species	[Species:48887] Homo sapiens
stId	uniprot:A6NI73
url	http://purl.uniprot.org/uniprot/A6NI73

Referrals

(referenceEntity)

[EntityWithAccessionedSequence:R-HSA-6786741] LILRA5 [plasma membrane]

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