Reactome | GBP1 binds actin

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10728148
displayName	GBP1 binds actin
eventOf	[Pathway:R-XTR-9953170] GBP-mediated host defense - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9956706] GBP1 binds actin - Homo sapiens
input	[Complex:R-XTR-201857] G-actin [cytosol] [DefinedSet:R-XTR-9947912-5] Homologues of S-farn-C589-GBP1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	GBP1 binds actin
output	[Complex:R-XTR-9956689] GBP1:G-actin [cytosol]
precedingEvent	[Reaction:R-XTR-9948016] FNTA:FNTB transfers farnesyl to GBP1 - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9956706
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-9953170] GBP-mediated host defense
(inferredTo)	[Reaction:R-HSA-9956706] GBP1 binds actin