Reactome | CHD and CDK2AP subunits are recruited to NuRD

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CHD and CDK2AP subunits are recruited to NuRD Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10727562
displayName	CHD and CDK2AP subunits are recruited to NuRD
eventOf	[Pathway:R-XTR-9937850] NuRD complex assembly - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-9944714] NuRD binds TCF19 at PCK1 gene - Xenopus tropicalis [Reaction:R-XTR-9944893] NuRD binds Ikaros family member proteins - Xenopus tropicalis [Reaction:R-XTR-9941744] PHF6 binds NuRD - Xenopus tropicalis [Reaction:R-XTR-9941697] ZNF827 and NR2C2,NR2F2 recruit NuRD to telomeric chromatin - Xenopus tropicalis [Reaction:R-XTR-9944706] NuRD binds TCF19 at FBP1 gene - Xenopus tropicalis [Reaction:R-XTR-9944712] NuRD binds TCF19 at G6PC gene - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-9940468] CHD and CDK2AP subunits are recruited to NuRD - Homo sapiens
input	[EntityWithAccessionedSequence:R-XTR-9940397] cdk2ap1 [nucleoplasm] [EntityWithAccessionedSequence:R-XTR-9940392] chd5 [nucleoplasm] [Complex:R-XTR-9940439] HDAC1, HDAC2:MTA1, MTA2, MTA3:RBBP4, RBBP7:MBD2, MBD3:GATAD2A, GATAD2B [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	CHD and CDK2AP subunits are recruited to NuRD
output	[Complex:R-XTR-9940443] NuRD [nucleoplasm]
precedingEvent	[Reaction:R-XTR-9940462] MBD2, MBD3 and GATAD2A, GATAD2B bind core NuRD complex - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9940468
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-9937850] NuRD complex assembly
(precedingEvent)	[Reaction:R-XTR-9944714] NuRD binds TCF19 at PCK1 gene [Reaction:R-XTR-9944893] NuRD binds Ikaros family member proteins [Reaction:R-XTR-9941744] PHF6 binds NuRD [Reaction:R-XTR-9941697] ZNF827 and NR2C2,NR2F2 recruit NuRD to telomeric chromatin [Reaction:R-XTR-9944706] NuRD binds TCF19 at FBP1 gene [Reaction:R-XTR-9944712] NuRD binds TCF19 at G6PC gene
(inferredTo)	[Reaction:R-HSA-9940468] CHD and CDK2AP subunits are recruited to NuRD