Reactome | AKAP8L binds MLL2 complex

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10725052
displayName	AKAP8L binds MLL2 complex
eventOf	[Pathway:R-XTR-9772755] Formation of WDR5-containing histone-modifying complexes - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9821366] AKAP8L binds MLL2 complex - Homo sapiens
input	[EntityWithAccessionedSequence:R-XTR-9821364] akap8l [nucleoplasm] [Complex:R-XTR-9676271] MLL2 complex [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	AKAP8L binds MLL2 complex
output	[Complex:R-XTR-9821365] MLL2 complex:AKAP8L [nucleoplasm]
precedingEvent	[Reaction:R-XTR-9676255] Formation of the MLL2 complex - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9821366
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-9772755] Formation of WDR5-containing histone-modifying complexes
(inferredTo)	[Reaction:R-HSA-9821366] AKAP8L binds MLL2 complex

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