Reactome | SLC22A1 transports Cipro into renal cell

Schema > Reaction > Entries

SLC22A1 transports Cipro into renal cell Show undefined attributes

catalystActivity	[CatalystActivity:10724824] transmembrane transporter activity of SLC22A1 [basolateral plasma membrane]
category	transition
compartment	[Compartment:984] extracellular region [Compartment:24778] basolateral plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10724826
displayName	SLC22A1 transports Cipro into renal cell
eventOf	[Pathway:R-XTR-9793528] Ciprofloxacin ADME - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9794523] SLC22A1 transports Cipro into renal cell - Homo sapiens
input	[SimpleEntity:R-ALL-9794119] Cipro [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC22A1 transports Cipro into renal cell
output	[SimpleEntity:R-ALL-9793625] Cipro [cytosol]
precedingEvent	[Reaction:R-XTR-9794475] Cipro:ALB dissociates - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9794523
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-9793528] Ciprofloxacin ADME
(inferredTo)	[Reaction:R-HSA-9794523] SLC22A1 transports Cipro into renal cell

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