Reactome | ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region

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ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region Show undefined attributes

catalystActivity	[CatalystActivity:10722229] bilirubin transmembrane transporter activity of ABCG2 tetramer [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10722231
displayName	ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region
eventOf	[Pathway:R-XTR-189483] Heme degradation - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9661417] ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [DefinedSet:R-ALL-5679042] BMG,BDG [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [DefinedSet:R-ALL-5679034] BMG,BDG [extracellular region] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9661417
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-189483] Heme degradation
(inferredTo)	[Reaction:R-HSA-9661417] ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region

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