Reactome | sGC stimulators bind sGC:NO

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10721352
displayName	sGC stimulators bind sGC:NO
eventOf	[Pathway:R-XTR-445355] Smooth Muscle Contraction - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9620456] sGC stimulators bind sGC:NO - Homo sapiens
input	[Complex:R-XTR-392141] Guanylate cyclase:NO [cytosol] [DefinedSet:R-ALL-9620451] sGC stimulators [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	sGC stimulators bind sGC:NO
output	[Complex:R-XTR-9620466] NO:sGC:sGC stimulators [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9620456
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-445355] Smooth Muscle Contraction
(inferredTo)	[Reaction:R-HSA-9620456] sGC stimulators bind sGC:NO

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