Reactome | ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3

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ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 Show undefined attributes

catalystActivity	[CatalystActivity:10720293] oxidoreductase activity, acting on single donors with incorporation of molecular oxygen of ALOX5 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10720544
displayName	ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3
eventOf	[Pathway:R-XTR-9026286] Biosynthesis of DPAn-3-derived protectins and resolvins - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9025999] ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 - Homo sapiens
input	[SimpleEntity:R-ALL-9026047] 17(S)-Hp-DPAn-3 [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3
output	[SimpleEntity:R-ALL-9026046] 16(S),17(S)-epoxy-DPAn-3 [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9025999
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-9026286] Biosynthesis of DPAn-3-derived protectins and resolvins
(inferredTo)	[Reaction:R-HSA-9025999] ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3

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