Reactome | Biosynthesis of aspirin-triggered D-series resolvins

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Biosynthesis of aspirin-triggered D-series resolvins Show undefined attributes

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10731280
displayName	Biosynthesis of aspirin-triggered D-series resolvins
eventOf	[Pathway:R-XTR-9018677] Biosynthesis of DHA-derived SPMs - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:81415] long-chain fatty acid biosynthetic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-XTR-9020259] ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA - Xenopus tropicalis [Reaction:R-XTR-9020251] ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA - Xenopus tropicalis [Reaction:R-XTR-9020256] ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA - Xenopus tropicalis [Reaction:R-XTR-9020278] ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA - Xenopus tropicalis [Reaction:R-XTR-9020252] LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 - Xenopus tropicalis [Reaction:R-XTR-9020270] LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-9020265] Biosynthesis of aspirin-triggered D-series resolvins - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Biosynthesis of aspirin-triggered D-series resolvins
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9020265
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-9018677] Biosynthesis of DHA-derived SPMs
(inferredTo)	[Pathway:R-HSA-9020265] Biosynthesis of aspirin-triggered D-series resolvins

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