Reactome | RHO GTPase cycle

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RHO GTPase cycle Show undefined attributes

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10730810
displayName	RHO GTPase cycle
eventOf	[Pathway:R-XTR-194315] Signaling by Rho GTPases - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:160228] regulation of small GTPase mediated signal transduction
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-XTR-8980692] RHOA GTPase cycle - Xenopus tropicalis [Pathway:R-XTR-9013026] RHOB GTPase cycle - Xenopus tropicalis [Pathway:R-XTR-9013106] RHOC GTPase cycle - Xenopus tropicalis [Pathway:R-XTR-9013404] RAC2 GTPase cycle - Xenopus tropicalis [Pathway:R-XTR-9013423] RAC3 GTPase cycle - Xenopus tropicalis [Pathway:R-XTR-9013408] RHOG GTPase cycle - Xenopus tropicalis [Pathway:R-XTR-9013148] CDC42 GTPase cycle - Xenopus tropicalis [Pathway:R-XTR-9013409] RHOJ GTPase cycle - Xenopus tropicalis [Pathway:R-XTR-9013406] RHOQ GTPase cycle - Xenopus tropicalis [Pathway:R-XTR-9013424] RHOV GTPase cycle - Xenopus tropicalis [Pathway:R-XTR-9035034] RHOF GTPase cycle - Xenopus tropicalis [Pathway:R-XTR-9706574] RHOBTB GTPase Cycle - Xenopus tropicalis [Pathway:R-XTR-9013407] RHOH GTPase cycle - Xenopus tropicalis [Pathway:R-XTR-9696273] RND1 GTPase cycle - Xenopus tropicalis [Pathway:R-XTR-9696264] RND3 GTPase cycle - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-9012999] RHO GTPase cycle - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	RHO GTPase cycle
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9012999
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-194315] Signaling by Rho GTPases
(inferredTo)	[Pathway:R-HSA-9012999] RHO GTPase cycle

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