Reactome | ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers

Schema > Reaction > Entries

ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10719418
displayName	ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers
eventOf	[Pathway:R-XTR-9018519] Estrogen-dependent gene expression - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-9011949] KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-9011952] ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers - Homo sapiens
input	[Complex:R-XTR-1254381] ESR1 dimer:ESTG [nucleoplasm] [EntityWithAccessionedSequence:R-XTR-3214396] kdm4b [nucleoplasm] [Complex:R-XTR-9011915] KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers
output	[Complex:R-XTR-9011913] KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm]
precedingEvent	[Reaction:R-XTR-8939201] ESR dimerizes - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9011952
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-9018519] Estrogen-dependent gene expression
(precedingEvent)	[Reaction:R-XTR-9011949] KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers
(inferredTo)	[Reaction:R-HSA-9011952] ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers

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