Reactome | E2F8 forms homodimers

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10718060
displayName	E2F8 forms homodimers
eventOf	[Pathway:R-XTR-6804116] TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8953037] E2F8 forms homodimers - Homo sapiens
input	2 × [EntityWithAccessionedSequence:R-XTR-8952990] e2f8 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	E2F8 forms homodimers
output	[Complex:R-XTR-8953035] E2F8 homodimer [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-8953037
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-6804116] TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
(inferredTo)	[Reaction:R-HSA-8953037] E2F8 forms homodimers

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