Reactome | PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter

Schema > Reaction > Entries

PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter Show undefined attributes

catalystActivity	[CatalystActivity:10715820] histone H3 methyltransferase activity of RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10715822
displayName	PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter
eventOf	[Pathway:R-XTR-8936459] RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8937113] PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter - Homo sapiens
input	4 × [SimpleEntity:R-ALL-77087] AdoMet [nucleoplasm] [Complex:R-XTR-8937114] RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter
output	4 × [SimpleEntity:R-ALL-77502] AdoHcy [nucleoplasm] [Complex:R-XTR-8937112] RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-8937113
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-8936459] RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
(inferredTo)	[Reaction:R-HSA-8937113] PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter

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