Reactome | NPC1:CHOL [lysosomal membrane]

Schema > Complex > Entries

compartment	[Compartment:17938] lysosomal membrane
consumedByEvent	[BlackBoxEvent:R-XTR-8876485] CHOL translocates from lysosome membrane to ER membrane - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10715179
displayName	NPC1:CHOL [lysosomal membrane]
hasComponent	[SimpleEntity:R-ALL-8876478] CHOL [lysosomal membrane] [EntityWithAccessionedSequence:R-XTR-5216153] npc1 [lysosomal membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-8876475] NPC1:CHOL [lysosomal membrane] - Homo sapiens
maxDepth	2
name	NPC1:CHOL
producedByEvent	[Reaction:R-XTR-8876484] NPC2 transfers CHOL to NPC1 - Xenopus tropicalis
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-8876475
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[BlackBoxEvent:R-XTR-8876485] CHOL translocates from lysosome membrane to ER membrane
(output)	[Reaction:R-XTR-8876484] NPC2 transfers CHOL to NPC1
(inferredTo)	[Complex:R-HSA-8876475] NPC1:CHOL [lysosomal membrane]

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