Reactome | B4GALNT1 dimer transfers GalNAc to gangliosides

Schema > Reaction > Entries

B4GALNT1 dimer transfers GalNAc to gangliosides Show undefined attributes

catalystActivity	[CatalystActivity:10713216] (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity of B4GALNT1 dimer [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10713218
displayName	B4GALNT1 dimer transfers GalNAc to gangliosides
eventOf	[Pathway:R-XTR-9840309] Glycosphingolipid biosynthesis - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-9845516] B3GALT4 transfers Gal to gangliosides - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-8856223] B4GALNT1 dimer transfers GalNAc to gangliosides - Homo sapiens
input	[DefinedSet:R-ALL-8856243] GD3,GM3,GT3,SM3,LacCer [Golgi membrane] [SimpleEntity:R-ALL-735700] UDP-GalNAc [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	B4GALNT1 dimer transfers GalNAc to gangliosides
output	[DefinedSet:R-ALL-8856242] GD2,GM2, GA2,GT2,SM2 [Golgi membrane] [SimpleEntity:R-ALL-425969] H+ [Golgi lumen] [SimpleEntity:R-ALL-205687] UDP [Golgi lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-8856223
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-9840309] Glycosphingolipid biosynthesis
(precedingEvent)	[Reaction:R-XTR-9845516] B3GALT4 transfers Gal to gangliosides
(inferredTo)	[Reaction:R-HSA-8856223] B4GALNT1 dimer transfers GalNAc to gangliosides

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