Reactome | PNPLA4 hydrolyzes TAG

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PNPLA4 hydrolyzes TAG Show undefined attributes

catalystActivity	[CatalystActivity:10711837] triacylglycerol lipase activity of PNPLA4 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10711839
displayName	PNPLA4 hydrolyzes TAG
eventOf	[Pathway:R-XTR-163560] Triglyceride catabolism - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8848338] PNPLA4 hydrolyzes TAG - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-549167] TAG [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PNPLA4 hydrolyzes TAG a triacylglycerol + H2O => a diacylglycerol + a fatty acid + H(+)
output	[SimpleEntity:R-ALL-76103] DAG [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-8876730] LCFA(-) [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-8848338
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-163560] Triglyceride catabolism
(inferredTo)	[Reaction:R-HSA-8848338] PNPLA4 hydrolyzes TAG

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