Reactome | CYP4A11 omega-hydroxylates DDCX

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CYP4A11 omega-hydroxylates DDCX Show undefined attributes

catalystActivity	[CatalystActivity:10656367] monooxygenase activity of Cytochrome P450 (CYP4A11 based) [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:17960] smooth endoplasmic reticulum
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10656369
displayName	CYP4A11 omega-hydroxylates DDCX
eventOf	[Pathway:R-XTR-211935] Fatty acids - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:534] fatty acid metabolic process
inferredFrom	[Reaction:R-HSA-76466] CYP4A11 omega-hydroxylates DDCX - Homo sapiens
input	[SimpleEntity:R-ALL-33549] DDCX [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-156540] H+ [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113601] NADPH [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113534] O2 [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	CYP4A11 omega-hydroxylates DDCX dodecanoic acid + O₂ + NADPH + H⁺ -> 12-hydroxydodecanoic acid + H₂O + NADP⁺
output	[SimpleEntity:R-ALL-42373] 12OH-DDCX [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113519] H2O [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113564] NADP+ [endoplasmic reticulum lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-76466
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-211935] Fatty acids
(inferredTo)	[Reaction:R-HSA-76466] CYP4A11 omega-hydroxylates DDCX

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