Reactome | Addition of the third nucleotide on the nascent transcript

Schema > BlackBoxEvent > Entries

Addition of the third nucleotide on the nascent transcript Show undefined attributes

catalystActivity	[CatalystActivity:10655983] DNA-directed RNA polymerase activity of RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm]
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10655985
displayName	Addition of the third nucleotide on the nascent transcript
eventOf	[Pathway:R-XTR-73776] RNA Polymerase II Promoter Escape - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-75850] Addition of the third nucleotide on the nascent transcript - Homo sapiens
input	[SimpleEntity:R-ALL-9757634] NTP [nucleoplasm] [Complex:R-XTR-109878] pol II transcription complex [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Addition of the third nucleotide on the nascent transcript
output	[Complex:R-XTR-75878] pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] [SimpleEntity:R-ALL-113541] PPi [nucleoplasm]
precedingEvent	[Reaction:R-XTR-75864] Newly Formed Phosphodiester Bond Stabilized and PPi Released - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-75850
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-73776] RNA Polymerase II Promoter Escape
(inferredTo)	[BlackBoxEvent:R-HSA-75850] Addition of the third nucleotide on the nascent transcript

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