Reactome | TPI1 dimer isomerizes GA3P to DHAP

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TPI1 dimer isomerizes GA3P to DHAP Show undefined attributes

catalystActivity	[CatalystActivity:10652598] triose-phosphate isomerase activity of TPI1 dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10652651
displayName	TPI1 dimer isomerizes GA3P to DHAP
eventOf	[Pathway:R-XTR-70263] Gluconeogenesis - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-71495] Aldolase tetramers convert GA3P and DHAP to F1,6PP - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-70481] TPI1 dimer isomerizes GA3P to DHAP - Homo sapiens
input	[SimpleEntity:R-ALL-29578] GA3P [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	TPI1 dimer isomerizes GA3P to DHAP D-glyceraldehyde 3-phosphate => dihydroxyacetone phosphate
output	[SimpleEntity:R-ALL-75970] DHAP [cytosol]
precedingEvent	[Reaction:R-XTR-70482] GAPDH tetramers reduce 1,3BPG to GA3P - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-70481
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-70263] Gluconeogenesis
(precedingEvent)	[Reaction:R-XTR-71495] Aldolase tetramers convert GA3P and DHAP to F1,6PP
(inferredTo)	[Reaction:R-HSA-70481] TPI1 dimer isomerizes GA3P to DHAP

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