Reactome | GPI dimer isomerizes G6P

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GPI dimer isomerizes G6P Show undefined attributes

catalystActivity	[CatalystActivity:10652626] glucose-6-phosphate isomerase activity of GPI dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10652628
displayName	GPI dimer isomerizes G6P
eventOf	[Pathway:R-XTR-70171] Glycolysis - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-532549] MPI isomerises Fru6P to Man6P - Xenopus tropicalis [Reaction:R-XTR-163751] D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate - Xenopus tropicalis [Reaction:R-XTR-163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Xenopus tropicalis [Reaction:R-XTR-71802] PFKFKB dimer phosphorylates Fru(6)P - Xenopus tropicalis [Reaction:R-XTR-70467] PFK tetramer phosphorylates Fru(6)P - Xenopus tropicalis [Reaction:R-XTR-449715] GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-70471] GPI dimer isomerizes G6P - Homo sapiens
input	[SimpleEntity:R-ALL-30537] G6P [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	GPI dimer isomerizes G6P alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate Glucose 6-phosphate is isomerized to form fructose-6-phosphate
output	[SimpleEntity:R-ALL-29512] Fru(6)P [cytosol]
precedingEvent	[Reaction:R-XTR-70420] HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P - Xenopus tropicalis [Reaction:R-XTR-5696021] ADPGK:Mg2+ phosphorylates Glc to G6P - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-70471
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-XTR-532549] MPI isomerises Fru6P to Man6P [Reaction:R-XTR-163751] D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate [Reaction:R-XTR-163764] D-fructose 6-phosphate + D-erythrose 4-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate [Reaction:R-XTR-71802] PFKFKB dimer phosphorylates Fru(6)P [Reaction:R-XTR-70467] PFK tetramer phosphorylates Fru(6)P [Reaction:R-XTR-449715] GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P
(hasEvent)	[Pathway:R-XTR-70171] Glycolysis
(inferredTo)	[Reaction:R-HSA-70471] GPI dimer isomerizes G6P