Reactome | Keratin filaments bind cell-cell adhesion complexes

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Keratin filaments bind cell-cell adhesion complexes Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10710842
displayName	Keratin filaments bind cell-cell adhesion complexes
eventOf	[Pathway:R-XTR-6805567] Keratinization - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6809393] Keratin filaments bind cell-cell adhesion complexes - Homo sapiens
input	[Complex:R-XTR-6814388] Desmosome [plasma membrane] [Polymer:R-XTR-6809668] Keratin tonofilament [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Keratin filaments bind cell-cell adhesion complexes
output	[Complex:R-XTR-6814735] Keratin tonofilament:Desmosome [plasma membrane]
precedingEvent	[Polymerisation:R-XTR-6806629] Formation of tonofilament bundles - Xenopus tropicalis
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-6809393
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-6805567] Keratinization
(inferredTo)	[Reaction:R-HSA-6809393] Keratin filaments bind cell-cell adhesion complexes

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