Reactome | Neurexins and neuroligins

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Neurexins and neuroligins Show undefined attributes

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10730968
displayName	Neurexins and neuroligins
eventOf	[Pathway:R-XTR-6794362] Protein-protein interactions at synapses - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-XTR-6794346] NRXNs bind NLGNs - Xenopus tropicalis [Reaction:R-XTR-6797974] LRRTMs bind NRXNs - Xenopus tropicalis [Reaction:R-XTR-6794355] Homer1,2,3 binds mGluR1a,5 - Xenopus tropicalis [Reaction:R-XTR-6794347] Homer1,2,3 dimerizes - Xenopus tropicalis [Reaction:R-XTR-6797554] ABP1 binds SHANK proteins - Xenopus tropicalis [Reaction:R-XTR-6797553] Protein 4.1 binds CASK - Xenopus tropicalis [Reaction:R-XTR-6797568] NRXNs bind CASK:Protein 4.1 - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-6794361] Neurexins and neuroligins - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Neurexins and neuroligins
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-6794361
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-6794362] Protein-protein interactions at synapses
(inferredTo)	[Pathway:R-HSA-6794361] Neurexins and neuroligins

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