Reactome | CSF3R binds CSF3 dimer

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10705702
displayName	CSF3R binds CSF3 dimer
eventOf	[Pathway:R-XTR-449836] Other interleukin signaling - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-8854738] CSF3 dimer:CSFR binds CSFR - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-6787737] CSF3R binds CSF3 dimer - Homo sapiens
input	[Complex:R-XTR-8854719] CSF3 dimer [extracellular region] [EntityWithAccessionedSequence:R-XTR-6787734] csf3r [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	CSF3R binds CSF3 dimer
output	[Complex:R-XTR-6787729] CSF3 dimer:CSF3R [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-6787737
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-449836] Other interleukin signaling
(precedingEvent)	[Reaction:R-XTR-8854738] CSF3 dimer:CSFR binds CSFR
(inferredTo)	[Reaction:R-HSA-6787737] CSF3R binds CSF3 dimer

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