Reactome | Downstream signaling of activated FGFR3

Schema > Pathway > Entries

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10729312
displayName	Downstream signaling of activated FGFR3
eventOf	[Pathway:R-XTR-5654741] Signaling by FGFR3 - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-XTR-5654706] FRS-mediated FGFR3 signaling - Xenopus tropicalis [Pathway:R-XTR-5654227] Phospholipase C-mediated cascade; FGFR3 - Xenopus tropicalis [Pathway:R-XTR-5654704] SHC-mediated cascade:FGFR3 - Xenopus tropicalis [Pathway:R-XTR-5654710] PI-3K cascade:FGFR3 - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-5654708] Downstream signaling of activated FGFR3 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Downstream signaling of activated FGFR3
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-5654708
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-5654741] Signaling by FGFR3
(inferredTo)	[Pathway:R-HSA-5654708] Downstream signaling of activated FGFR3

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