Reactome | VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10696385] protein tyrosine kinase activity of VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-XTR-5218812] FYN phosphorylates PAK2 - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10696384
displayName	VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane]
hasComponent	[Complex:R-XTR-5218800] p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane] [Complex:R-XTR-5218780] VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:p-S21,Y420-FYN [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-5218792] VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] - Homo sapiens
maxDepth	6
name	VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP
producedByEvent	[Reaction:R-XTR-5218814] PAK2 autophorylates - Xenopus tropicalis
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-5218792
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-XTR-5218812] FYN phosphorylates PAK2
(physicalEntity)	[CatalystActivity:10696385] protein tyrosine kinase activity of VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane]
(output)	[Reaction:R-XTR-5218814] PAK2 autophorylates
(inferredTo)	[Complex:R-HSA-5218792] VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane]

Cite Us!