Reactome | SUMOylation of DNA replication proteins

Schema > Pathway > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10730694
displayName	SUMOylation of DNA replication proteins
eventOf	[Pathway:R-XTR-3108232] SUMO E3 ligases SUMOylate target proteins - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[BlackBoxEvent:R-XTR-4655355] RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) - Xenopus tropicalis [Reaction:R-XTR-4641350] PIAS4 SUMOylates TOP2A with SUMO2,3 - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-4615885] SUMOylation of DNA replication proteins - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	SUMOylation of DNA replication proteins
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-4615885
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-3108232] SUMO E3 ligases SUMOylate target proteins
(inferredTo)	[Pathway:R-HSA-4615885] SUMOylation of DNA replication proteins

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