Reactome | VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane]

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VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-XTR-4420164] VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] - Xenopus tropicalis [Complex:R-XTR-4420171] VEGFA:p-6Y-VEGFR2:SHC2 [plasma membrane] - Xenopus tropicalis
consumedByEvent	[Reaction:R-XTR-4420107] p-6Y-VEGFR2 binds SHC-transforming protein 2 - Xenopus tropicalis [Reaction:R-XTR-5218815] p-6Y-VEGFR2 binds NCK - Xenopus tropicalis [Reaction:R-XTR-5218818] Integrin alphaVbeta3 binds p-6Y-VEGFR2 - Xenopus tropicalis [Reaction:R-XTR-4420099] p-6Y-VEGFR2 binds SHB - Xenopus tropicalis [Reaction:R-XTR-4420143] p-6Y-VEGFR2 binds SH2D2A - Xenopus tropicalis [Reaction:R-XTR-4420153] p-6Y-VEGFR2 binds PLCG1 - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10694632
displayName	VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane]
hasComponent	[Complex:R-XTR-4420096] p-6Y-VEGFR2 dimer [plasma membrane] [Complex:R-XTR-4420158] VEGFA-165 dimer [extracellular region]
inDisease	false
inferredFrom	[Complex:R-HSA-4420101] VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane] - Homo sapiens
maxDepth	3
name	VEGFA dimer:p-6Y-VEGFR2 dimer
producedByEvent	[Reaction:R-XTR-4420202] PLCG1 disassociates from VEGFR2 and translocate to PM - Xenopus tropicalis [Reaction:R-XTR-4420117] VEGFR2 autophosphorylates - Xenopus tropicalis
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-4420101
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-XTR-4420107] p-6Y-VEGFR2 binds SHC-transforming protein 2 [Reaction:R-XTR-5218815] p-6Y-VEGFR2 binds NCK [Reaction:R-XTR-5218818] Integrin alphaVbeta3 binds p-6Y-VEGFR2 [Reaction:R-XTR-4420099] p-6Y-VEGFR2 binds SHB [Reaction:R-XTR-4420143] p-6Y-VEGFR2 binds SH2D2A [Reaction:R-XTR-4420153] p-6Y-VEGFR2 binds PLCG1
(hasComponent)	[Complex:R-XTR-4420171] VEGFA:p-6Y-VEGFR2:SHC2 [plasma membrane] [Complex:R-XTR-5218798] VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2 [plasma membrane] [Complex:R-XTR-4420196] VEGFA dimer:p-6Y-VEGFR2 dimer:SHB [plasma membrane] [Complex:R-XTR-5218779] VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane] [Complex:R-XTR-4420164] VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] [Complex:R-XTR-4420137] VEGFA dimer:p-6Y-VEGFR2 dimer:SH2D2A [plasma membrane] [Complex:R-XTR-5218777] VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K [plasma membrane] [Complex:R-XTR-4420203] VEGFA dimer:p-6Y-VEGFR2 dimer:PLCG1 [plasma membrane] [Complex:R-XTR-4420110] VEGFA dimer:p-6Y-VEGFR2 dimer:p-4Y-PLCG1 [plasma membrane]
(output)	[Reaction:R-XTR-4420202] PLCG1 disassociates from VEGFR2 and translocate to PM [Reaction:R-XTR-4420117] VEGFR2 autophosphorylates
(inferredTo)	[Complex:R-HSA-4420101] VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane]

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