Reactome | Sodium/Proton exchangers

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Sodium/Proton exchangers Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10729942
displayName	Sodium/Proton exchangers
eventOf	[Pathway:R-XTR-425410] Metal ion SLC transporters - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:1301070] sodium ion transmembrane transport
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-XTR-425994] Na+/H+ exchanger transport (at cell membrane) - Xenopus tropicalis [Reaction:R-XTR-425983] SLC9A6,7 exchange Na+ for H+ across the early endosome membrane - Xenopus tropicalis [Reaction:R-XTR-426015] Na+/H+ exchanger transport (at trans-golgi membrane) - Xenopus tropicalis [Reaction:R-XTR-425965] SLC9A9 exchanges Na+ for H+ across the late endosome membrane - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-425986] Sodium/Proton exchangers - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Sodium/Proton exchangers
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-425986
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-425410] Metal ion SLC transporters
(inferredTo)	[Pathway:R-HSA-425986] Sodium/Proton exchangers