Reactome | Proglucagon translocates from the ER Lumen to secretory granules

Schema > BlackBoxEvent > Entries

Proglucagon translocates from the ER Lumen to secretory granules Show undefined attributes

category	omitted
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:1462052] secretory granule lumen
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10673315
displayName	Proglucagon translocates from the ER Lumen to secretory granules
eventOf	[Pathway:R-XTR-381771] Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-421416] Proglucagon translocates from the ER Lumen to secretory granules - Homo sapiens
input	[EntityWithAccessionedSequence:R-XTR-381774] gcg [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	Proglucagon translocates from the ER Lumen to secretory granules
output	[EntityWithAccessionedSequence:R-XTR-421418] gcg [secretory granule lumen]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-421416
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-381771] Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
(inferredTo)	[BlackBoxEvent:R-HSA-421416] Proglucagon translocates from the ER Lumen to secretory granules

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