Reactome | Phosphorylation of CRMPs by Cdk5

Schema > Reaction > Entries

Phosphorylation of CRMPs by Cdk5 Show undefined attributes

catalystActivity	[CatalystActivity:10672356] protein serine/threonine kinase activity of Sema3A:Nrp-1:PlexinA:Fyn:pCdk5 [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10672358
displayName	Phosphorylation of CRMPs by Cdk5
eventOf	[Pathway:R-XTR-399956] CRMPs in Sema3A signaling - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-399951] Phosphorylation of CRMPs by GSK3beta - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-399944] Phosphorylation of CRMPs by Cdk5 - Homo sapiens
input	4 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-XTR-399843] CRMP's tetramers [cytosol] [Complex:R-XTR-399868] Sema3A:Nrp-1:PlexinA:Fyn:pCdk5 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Phosphorylation of CRMPs by Cdk5
output	4 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-XTR-399867] Sema3A:Nrp-1:PlexinA:Fyn:Cdk5:pCRMP's [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-399944
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-399956] CRMPs in Sema3A signaling
(precedingEvent)	[Reaction:R-XTR-399951] Phosphorylation of CRMPs by GSK3beta
(inferredTo)	[Reaction:R-HSA-399944] Phosphorylation of CRMPs by Cdk5

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