Reactome | Semaphorin interactions

Schema > Pathway > Entries

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10729870
displayName	Semaphorin interactions
eventOf	[Pathway:R-XTR-422475] Axon guidance - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-XTR-400685] Sema4D in semaphorin signaling - Xenopus tropicalis [Pathway:R-XTR-399954] Sema3A PAK dependent Axon repulsion - Xenopus tropicalis [Pathway:R-XTR-399956] CRMPs in Sema3A signaling - Xenopus tropicalis [Pathway:R-XTR-416700] Other semaphorin interactions - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-373755] Semaphorin interactions - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	Semaphorin interactions
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-373755
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-422475] Axon guidance
(hasEncapsulatedEvent)	[Pathway:R-XTR-8848021] Signaling by PTK6 [Pathway:R-XTR-5627117] RHO GTPases Activate ROCKs
(inferredTo)	[Pathway:R-HSA-373755] Semaphorin interactions