Reactome | SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane

Schema > Reaction > Entries

SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane Show undefined attributes

catalystActivity	[CatalystActivity:10693164] glucose 6-phosphate:phosphate antiporter activity of SLC37A1,2 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10693166
displayName	SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane
eventOf	[Pathway:R-XTR-70263] Gluconeogenesis - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:24959] glucose-6-phosphate transport
inferredFrom	[Reaction:R-HSA-3257122] SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane - Homo sapiens
input	[SimpleEntity:R-ALL-30537] G6P [cytosol] [SimpleEntity:R-ALL-113551] Pi [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane alpha-D-glucose 6-phosphate (cytosol) + orthophosphate (ER lumen) => alpha-D-glucose 6-phosphate (ER lumen) + orthophosphate (cytosol) (SLC37A1 or SLC37A2)
output	[SimpleEntity:R-ALL-113782] G6P [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-3257122
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-70263] Gluconeogenesis
(inferredTo)	[Reaction:R-HSA-3257122] SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane

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