Reactome | HDACs deacetylate histones

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HDACs deacetylate histones Show undefined attributes

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10730654
displayName	HDACs deacetylate histones
eventOf	[Pathway:R-XTR-3247509] Chromatin modifying enzymes - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-XTR-3769447] HDAC1:2-containing complex deacetylate histones - Xenopus tropicalis [Reaction:R-XTR-9679787] HDAC1:2-containing complex binds HDAC2 Inhibitors - Xenopus tropicalis [Reaction:R-XTR-3777129] HDAC3 containing complexes deacetylate histone - Xenopus tropicalis [Reaction:R-XTR-3782637] HDAC8 deacetylates histones - Xenopus tropicalis [Reaction:R-XTR-3782655] HDAC10 deacetylates histone - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-3214815] HDACs deacetylate histones - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	HDACs deacetylate histones
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-3214815
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-3247509] Chromatin modifying enzymes
(inferredTo)	[Pathway:R-HSA-3214815] HDACs deacetylate histones

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