Reactome | p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10691598] protein tyrosine kinase activity of p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-XTR-2730858] Autophosphorylation of BTK/ITK - Xenopus tropicalis
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10691508
displayName	p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane]
hasComponent	[Complex:R-XTR-2424460] p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] [CandidateSet:R-XTR-2685651] p-TEC kinases [cytosol] [SimpleEntity:R-ALL-179838] PI(3,4,5)P3 [plasma membrane] [DefinedSet:R-XTR-430172] VAV1,2,3 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-2685675] p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane] - Homo sapiens
maxDepth	6
name	p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3
schemaClass	Complex
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-2685675
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-XTR-2730858] Autophosphorylation of BTK/ITK
(physicalEntity)	[CatalystActivity:10691598] protein tyrosine kinase activity of p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane]
(inferredTo)	[Complex:R-HSA-2685675] p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane]

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